Gene detail

QM1_RS02130

Histidine kinase, Classic

Clostridioides difficile DA00212 · GCF_000450465

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450465#QM1_RS02130Stable P2CS identifier used across views.
GenomeGCF_000450465Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557910Run 6 · 376 sequences · id 100% · cov 80%
External referencesWP_021366129.1 · A0A069AZ83 · MIST4 QM1_RS02130RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QM1_RS02130
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000715:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000548:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.16e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000715:152:70:69#HisKA:164:0.0000000548:217:54:64#HATPase_c:278:1.16e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450465::NZ_AVJV01000016.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15872-17694Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQM1_0428RefSeq proteinWP_021366129.1
Context group IDGCF_000450465::NZ_AVJV01000016.1::G00006
Context members
QM1_RS02130QM1_RS02135
Partner locus tags
QM1_RS02130QM1_RS02135
Partner old locus tags
QM1_0428QM1_0429
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366129.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AZ83Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AZ83_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQM1_RS02130Primary locus identifier stored in the genes table.
Old locus tagQM1_0428Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJV01000016.1Sequence record reported by the local genomic context database.
Genomic interval15 872-17 032 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 872-17 694 ntGCF_000450465::NZ_AVJV01000016.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450465::NZ_AVJV01000016.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJV01000016.1All displayed genes belong to this local TCS context.
Neighborhood span15 872-17 694 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 872 nt17 694 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QM1_RS02130GCF_000450465#QM1_RS02130
HKClassicCurrent focus

15 872-17 032 nt · Reverse (-)

Old locus QM1_0428RefSeq WP_021366129.1
QM1_RS02135GCF_000450465#QM1_RS02135
RROmpR

17 020-17 694 nt · Reverse (-)

Old locus QM1_0429RefSeq WP_009895528.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557910Run 6 · HK · 376 sequences
Representative sequenceGCF_000448765#QC5_RS02270Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557910

Simplified PFAM architecture for HKOC_2557910

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557910
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS02270

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 347 · GCF_000450465
AssemblyASM45046v2 · Contighaploid
Genome composition4 149 547 bp · 28,0% GCClostridioides difficile DA00212
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key