Gene detail

QKW_RS14695

Histidine kinase, Classic

Clostridioides difficile DA00210 · GCF_000450425

ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450425#QKW_RS14695Stable P2CS identifier used across views.
GenomeGCF_000450425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1468511Run 6 · 180 sequences · id 100% · cov 80%
External referencesWP_021368000.1 · A0A9X8RJ55 · MIST4 QKW_RS14695RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
His_kinase: 305-376 aa (72 aa)1HATPase_c: 396-496 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw tokenHis_kinase:305:9.94e-25:376:72:80
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw tokenHATPase_c:396:0.00000314:496:107:109
  • Raw architecture: His_kinase:305:9.94e-25:376:72:80#HATPase_c:396:0.00000314:496:107:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450425::NZ_AVJT01000078.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span163995-166312Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKW_2997RefSeq proteinWP_021368000.1
Context group IDGCF_000450425::NZ_AVJT01000078.1::G00045
Context members
QKW_RS14690QKW_RS14695
Partner locus tags
QKW_RS14690QKW_RS14695
Partner old locus tags
QKW_2996QKW_2997
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021368000.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RJ55Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RJ55_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKW_RS14695Primary locus identifier stored in the genes table.
Old locus tagQKW_2997Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJT01000078.1Sequence record reported by the local genomic context database.
Genomic interval164 807-166 312 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span163 995-166 312 ntGCF_000450425::NZ_AVJT01000078.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450425::NZ_AVJT01000078.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJT01000078.1All displayed genes belong to this local TCS context.
Neighborhood span163 995-166 312 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
163 995 nt166 312 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QKW_RS14690GCF_000450425#QKW_RS14690
RRunclassified

163 995-164 693 nt · Reverse (-)

Old locus QKW_2996RefSeq WP_003436119.1
QKW_RS14695GCF_000450425#QKW_RS14695
HKClassicCurrent focus

164 807-166 312 nt · Reverse (-)

Old locus QKW_2997RefSeq WP_021368000.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1468511Run 6 · HK · 180 sequences
Representative sequenceGCF_000448805#QKI_RS15415Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1468511

Simplified PFAM architecture for HKOC_1468511

PFAM domain coverage: 136 / 501 aa (27.1%)

1 aa501 aa
Cupin_2: 35-96 aaCupin_2His_kinase: 303-376 aaHis_kinase
Cupin_2His_kinase
  • Simplified architecture: Cupin_2 + His_kinase
  • Raw architecture: Cupin_2[35-96] | His_kinase[303-376]
  • Domain count: 2
  • Matched identifier: HKOC_1468511
  • Positioned domains: Cupin_2 35-96 ; His_kinase 303-376
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS15415

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 180 total members. Page 1 / 4.

GCF_000448805#QKI_RS15415 (representative)
QKI_RS15415 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000448925#QC7_RS14885
QC7_RS14885 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000449125#QCQ_RS14885
QCQ_RS14885 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000449365#QEQ_RS14725
QEQ_RS14725 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000450265#QKE_RS14815
QKE_RS14815 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000450425#QKW_RS14695
QKW_RS14695 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000450905#QQI_RS13750
QQI_RS13750 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000451285#QEC_RS14315
QEC_RS14315 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000451365#QOO_RS15955
QOO_RS15955 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000452045#QUM_RS14965
QUM_RS14965 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000452425#QE3_RS15755
QE3_RS15755 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000473665#QUO_RS15155
QUO_RS15155 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000530325#BN178_RS15015
BN178_RS15015 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000530415#BN179_RS14370
BN179_RS14370 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_000530475#BN180_RS14085
BN180_RS14085 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_001577795#TW87_RS17430
TW87_RS17430 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_001971985#BER31_RS15700
BER31_RS15700 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_001972165#BER46_RS15505
BER46_RS15505 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_002301395#BGU18_RS02105
BGU18_RS02105 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_002301495#BGU26_RS00640
BGU26_RS00640 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_002303585#BGU69_RS03735
BGU69_RS03735 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_002939365#AWI45_RS09820
AWI45_RS09820 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_002940845#AWN79_RS15395
AWN79_RS15395 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_003013435#C7R55_RS11365
C7R55_RS11365 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_003862705#EGM05_RS07355
EGM05_RS07355 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_003862735#EGM03_RS05910
EGM03_RS05910 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_003863155#EGM04_RS04610
EGM04_RS04610 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004313905#E0N76_RS18125
E0N76_RS18125 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314025#E0N91_RS16535
E0N91_RS16535 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314085#E0O09_RS02095
E0O09_RS02095 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314125#E0N92_RS17325
E0N92_RS17325 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314445#E0O24_RS03660
E0O24_RS03660 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314625#E0O43_RS15605
E0O43_RS15605 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314705#E0O49_RS04500
E0O49_RS04500 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314885#E0O59_RS00755
E0O59_RS00755 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004314985#E0O69_RS02690
E0O69_RS02690 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004315025#E0O81_RS00305
E0O81_RS00305 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004315365#E0P39_RS05220
E0P39_RS05220 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004316445#E0Q31_RS03705
E0Q31_RS03705 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004316485#E0P95_RS00650
E0P95_RS00650 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004316785#E0Q15_RS02450
E0Q15_RS02450 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004318765#E0R20_RS14290
E0R20_RS14290 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_004319825#E0R80_RS18825
E0R80_RS18825 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_006380975#DA424_RS15840
DA424_RS15840 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007000655#D1N81_RS14410
D1N81_RS14410 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007000755#D1N77_RS16865
D1N77_RS16865 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007000785#D1N76_RS12920
D1N76_RS12920 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007000885#D1N72_RS03320
D1N72_RS03320 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007001005#D1N65_RS03635
D1N65_RS03635 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55
GCF_007001035#D1N63_RS00650
D1N63_RS00650 · HK · Classic
RefSeq: WP_021368000.1
UniProt: A0A9X8RJ55

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 345 · GCF_000450425
AssemblyASM45042v2 · Contighaploid
Genome composition4 250 589 bp · 28,5% GCClostridioides difficile DA00210
Signal transduction countsGenes 98 · HK 46 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key