Gene detail

QKW_RS10935

Histidine kinase, Classic

Clostridioides difficile DA00210 · GCF_000450425

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450425#QKW_RS10935Stable P2CS identifier used across views.
GenomeGCF_000450425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2216343Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_032541997.1 · A0A9X8RGJ7 · MIST4 QKW_RS10935RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-424 aa (118 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000151:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:1.4e-18:424:119:109
  • Raw architecture: HisKA:196:0.0000000000151:260:65:64#HATPase_c:307:1.4e-18:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450425::NZ_AVJT01000067.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span34939-36868Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKW_2235RefSeq proteinWP_032541997.1
Context group IDGCF_000450425::NZ_AVJT01000067.1::G00035
Context members
QKW_RS10935QKW_RS10940
Partner locus tags
QKW_RS10935QKW_RS10940
Partner old locus tags
QKW_2235QKW_2236
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_032541997.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RGJ7Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RGJ7_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKW_RS10935Primary locus identifier stored in the genes table.
Old locus tagQKW_2235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJT01000067.1Sequence record reported by the local genomic context database.
Genomic interval34 939-36 216 nt1 278 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span34 939-36 868 ntGCF_000450425::NZ_AVJT01000067.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450425::NZ_AVJT01000067.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJT01000067.1All displayed genes belong to this local TCS context.
Neighborhood span34 939-36 868 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 939 nt36 868 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QKW_RS10935GCF_000450425#QKW_RS10935
HKClassicCurrent focus

34 939-36 216 nt · Reverse (-)

Old locus QKW_2235RefSeq WP_032541997.1
QKW_RS10940GCF_000450425#QKW_RS10940
RROmpR

36 200-36 868 nt · Reverse (-)

Old locus QKW_2236RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2216343Run 6 · HK · 8 sequences
Representative sequenceGCF_000450425#QKW_RS10935The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2216343

Simplified PFAM architecture for HKOC_2216343

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2216343
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450425#QKW_RS10935

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 8 over 8 total members. Page 1 / 1.

GCF_000450425#QKW_RS10935 (representative)
QKW_RS10935 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_037920665#WIR68_RS11385
WIR68_RS11385 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900095995#DK447_RS03575
DK447_RS03575 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900165125#B2A99_RS02825
B2A99_RS02825 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900165155#B2B16_RS07705
B2B16_RS07705 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900165215#B2B92_RS03360
B2B92_RS03360 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900165295#B2A87_RS10635
B2A87_RS10635 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7
GCF_900166415#B2B80_RS00835
B2B80_RS00835 · HK · Classic
RefSeq: WP_032541997.1
UniProt: A0A9X8RGJ7

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 345 · GCF_000450425
AssemblyASM45042v2 · Contighaploid
Genome composition4 250 589 bp · 28,5% GCClostridioides difficile DA00210
Signal transduction countsGenes 98 · HK 46 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key