Gene detail

QKU_RS03120

Histidine kinase, CheA

Clostridioides difficile DA00203 · GCF_000450405

ClassHKTypeCheALength700 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000450405#QKU_RS03120Stable P2CS identifier used across views.
GenomeGCF_000450405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0768912Run 6 · 527 sequences · id 100% · cov 80%
External referencesWP_011860851.1 · Q188Y5 · MIST4 QKU_RS03120RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length700 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage441 / 700 aa (63.0%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa700 aa
Hpt: 3-106 aa (104 aa)1H-kinase_dim: 312-373 aa (62 aa)2HATPase_c: 420-559 aa (140 aa)3CheW: 564-698 aa (135 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw tokenHpt:3:0.00000000000000999:106:104:84
2 H-kinase_dim#2
312-373 aa · 62 aa · 8.9% of protein
Raw tokenH-kinase_dim:312:0.00000000000000438:373:67:67
3 HATPase_c#3
420-559 aa · 140 aa · 20.0% of protein
Raw tokenHATPase_c:420:1.65e-17:559:140:109
4 CheW#4
564-698 aa · 135 aa · 19.3% of protein
Raw tokenCheW:564:1.89e-22:698:136:138
  • Raw architecture: Hpt:3:0.00000000000000999:106:104:84#H-kinase_dim:312:0.00000000000000438:373:67:67#HATPase_c:420:1.65e-17:559:140:109#CheW:564:1.89e-22:698:136:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000450405::NZ_AVJS01000008.1::G00009
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span253513-255615Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKU_0615RefSeq proteinWP_011860851.1
Context group IDGCF_000450405::NZ_AVJS01000008.1::G00009
Context members
QKU_RS03120
Partner locus tags
QKU_RS03120
Partner old locus tags
QKU_0615
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011860851.1Primary protein accession used for annex mappings.
UniProt accessionQ188Y5Primary UniProt accession resolved in the annex database.
UniProt IDQ188Y5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKU_RS03120Primary locus identifier stored in the genes table.
Old locus tagQKU_0615Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJS01000008.1Sequence record reported by the local genomic context database.
Genomic interval253 513-255 615 nt2 103 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span253 513-255 615 ntGCF_000450405::NZ_AVJS01000008.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450405::NZ_AVJS01000008.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJS01000008.1All displayed genes belong to this local TCS context.
Neighborhood span253 513-255 615 nt2 103 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
253 513 nt255 615 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QKU_RS03120GCF_000450405#QKU_RS03120
HKCheACurrent focus

253 513-255 615 nt · Forward (+)

Old locus QKU_0615RefSeq WP_011860851.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0768912Run 6 · HK · 527 sequences
Representative sequenceGCF_000009205#CD630_RS03265Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0768912

Simplified PFAM architecture for HKOC_0768912

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0768912
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS03265

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 527 total members. Page 1 / 11.

GCF_000009205#CD630_RS03265 (representative)
CD630_RS03265 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000448885#QAU_RS02655
QAU_RS02655 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000448905#QAY_RS02605
QAY_RS02605 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449005#QCE_RS02525
QCE_RS02525 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449145#QCS_RS02445
QCS_RS02445 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449165#QCU_RS02520
QCU_RS02520 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449325#QEM_RS17240
QEM_RS17240 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449345#QEO_RS03240
QEO_RS03240 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449405#QEU_RS02540
QEU_RS02540 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449445#QEY_RS02340
QEY_RS02340 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449505#QG5_RS03875
QG5_RS03875 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449565#QMI_RS02890
QMI_RS02890 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449625#QMM_RS02465
QMM_RS02465 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449765#QGU_RS03030
QGU_RS03030 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449865#QI7_RS07345
QI7_RS07345 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449885#QIA_RS03560
QIA_RS03560 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000449905#QIC_RS02750
QIC_RS02750 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450065#QIU_RS02995
QIU_RS02995 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450185#QK7_RS02970
QK7_RS02970 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450205#QK9_RS02775
QK9_RS02775 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450285#QKG_RS02425
QKG_RS02425 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450325#QKM_RS02305
QKM_RS02305 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450405#QKU_RS03120
QKU_RS03120 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450465#QM1_RS02355
QM1_RS02355 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450605#QME_RS03170
QME_RS03170 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450745#QO3_RS02745
QO3_RS02745 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450825#QOG_RS02470
QOG_RS02470 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450865#QOK_RS02580
QOK_RS02580 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450885#QOM_RS02420
QOM_RS02420 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000450945#QQM_RS02755
QQM_RS02755 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451405#QQ9_RS02815
QQ9_RS02815 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451425#QOY_RS02530
QOY_RS02530 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451445#QOQ_RS02715
QOQ_RS02715 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451485#QQ7_RS02530
QQ7_RS02530 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451525#QQC_RS02795
QQC_RS02795 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451625#QQY_RS02535
QQY_RS02535 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451645#QS1_RS03130
QS1_RS03130 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451685#QS5_RS02635
QS5_RS02635 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451705#QS7_RS15875
QS7_RS15875 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451725#QS9_RS02615
QS9_RS02615 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000451845#QSY_RS02665
QSY_RS02665 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000530595#BN185_RS02540
BN185_RS02540 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000530835#BN170_RS02580
BN170_RS02580 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000531225#BN184_RS02935
BN184_RS02935 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000531385#BN169_RS02700
BN169_RS02700 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000531505#BN172_RS02660
BN172_RS02660 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000531595#BN171_RS02580
BN171_RS02580 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000531715#BN191_RS02885
BN191_RS02885 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000828225#SE46_RS15440
SE46_RS15440 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5
GCF_000828235#SE44_RS16175
SE44_RS16175 · HK · CheA
RefSeq: WP_011860851.1
UniProt: Q188Y5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 344 · GCF_000450405
AssemblyASM45040v2 · Contighaploid
Genome composition4 153 521 bp · 29,0% GCClostridioides difficile DA00203
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key