Gene detail

QKM_RS08210

Response regulator NtrC family

Clostridioides difficile DA00193 · GCF_000450325

ClassRRTypeNtrCLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450325#QKM_RS08210Stable P2CS identifier used across views.
GenomeGCF_000450325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0334040Run 7 · 43 sequences · id 100% · cov 80%
External referencesWP_021369522.1 · MIST4 QKM_RS08210RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 440 aa (61.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QKM_RS08210
Domain-by-domain annotation3 items
1 Response_reg#1
3-114 aa · 112 aa · 25.5% of protein
Raw tokenResponse_reg:3:1.01e-25:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 27.0% of protein
Raw tokenAAA_5:157:0.00000000272:275:128:135
3 HTH_8#3
398-437 aa · 40 aa · 9.1% of protein
Raw tokenHTH_8:398:0.000000000178:437:40:40
  • Raw architecture: Response_reg:3:1.01e-25:114:112:111#AAA_5:157:0.00000000272:275:128:135#HTH_8:398:0.000000000178:437:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450325::NZ_AVJO01000040.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18144-21460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKM_1649RefSeq proteinWP_021369522.1
Context group IDGCF_000450325::NZ_AVJO01000040.1::G00027
Context members
QKM_RS08205QKM_RS08210
Partner locus tags
QKM_RS08205QKM_RS08210
Partner old locus tags
QKM_1648QKM_1649
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021369522.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKM_RS08210Primary locus identifier stored in the genes table.
Old locus tagQKM_1649Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJO01000040.1Sequence record reported by the local genomic context database.
Genomic interval20 138-21 460 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 144-21 460 ntGCF_000450325::NZ_AVJO01000040.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450325::NZ_AVJO01000040.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJO01000040.1All displayed genes belong to this local TCS context.
Neighborhood span18 144-21 460 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 144 nt21 460 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QKM_RS08205GCF_000450325#QKM_RS08205
HKClassic

18 144-20 138 nt · Forward (+)

Old locus QKM_1648RefSeq WP_021381296.1
QKM_RS08210GCF_000450325#QKM_RS08210
RRNtrCCurrent focus

20 138-21 460 nt · Forward (+)

Old locus QKM_1649RefSeq WP_021369522.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0334040Run 7 · RR · 43 sequences
Representative sequenceGCF_000449005#QCE_RS08590Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0334040

Simplified PFAM architecture for RROC_0334040

PFAM domain coverage: 387 / 440 aa (88.0%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regResponse_reg: 3-113 aaResponse_regSigma54_activat: 136-300 aaSigma54_activatSigma54_activat: 136-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14AAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[136-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0334040
  • Positioned domains: Response_reg 3-113 ; Response_reg 3-113 ; Sigma54_activat 136-300 ; Sigma54_activat 136-300 ; AAA_lid_14 306-375 ; AAA_lid_14 306-375 ; HTH_8 397-437 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449005#QCE_RS08590

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 340 · GCF_000450325
AssemblyASM45032v2 · Contighaploid
Genome composition3 969 329 bp · 28,5% GCClostridioides difficile DA00193
Signal transduction countsGenes 99 · HK 46 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key