1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw token
His_kinase:305:9.94e-25:376:72:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QKE_RS14815
Histidine kinase, Classic
Clostridioides difficile DA00174 · GCF_000450265
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450265#QKE_RS14815Stable P2CS identifier used across views.
GenomeGCF_000450265Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw token
HATPase_c:396:0.00000314:496:107:109- Raw architecture: His_kinase:305:9.94e-25:376:72:80#HATPase_c:396:0.00000314:496:107:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000450265::NZ_AVJK01000100.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1497-3814Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKE_3045RefSeq proteinWP_021368000.1
Context group ID
GCF_000450265::NZ_AVJK01000100.1::G00045Context members
QKE_RS14810QKE_RS14815
Partner locus tags
QKE_RS14810QKE_RS14815
Partner old locus tags
QKE_3044QKE_3045
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021368000.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RJ55Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RJ55_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQKE_RS14815Primary locus identifier stored in the genes table.
Old locus tagQKE_3045Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJK01000100.1Sequence record reported by the local genomic context database.
Genomic interval2 309-3 814 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 497-3 814 ntGCF_000450265::NZ_AVJK01000100.1::G00045
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000450265::NZ_AVJK01000100.1::G00045Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJK01000100.1All displayed genes belong to this local TCS context.
Neighborhood span1 497-3 814 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 497 nt3 814 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QKE_RS14810GCF_000450265#QKE_RS14810
RRunclassified
1 497-2 195 nt · Reverse (-)
QKE_RS14815GCF_000450265#QKE_RS14815
HKClassicCurrent focus
2 309-3 814 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448805#QKI_RS15415Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1468511
Simplified PFAM architecture for HKOC_1468511
PFAM domain coverage: 136 / 501 aa (27.1%)
1 aa501 aa
Cupin_2His_kinase
- Simplified architecture: Cupin_2 + His_kinase
- Raw architecture: Cupin_2[35-96] | His_kinase[303-376]
- Domain count: 2
- Matched identifier: HKOC_1468511
- Positioned domains: Cupin_2 35-96 ; His_kinase 303-376
Cluster members and taxonomy
Representative gene: GCF_000448805#QKI_RS15415
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 336 · GCF_000450265
AssemblyASM45026v2 · Contighaploid
Genome composition4 068 098 bp · 28,5% GCClostridioides difficile DA00174
Signal transduction countsGenes 95 · HK 44 · RR 51CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key