Gene detail

QKC_RS13495

Histidine kinase, Classic

Clostridioides difficile DA00167 · GCF_000450245

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450245#QKC_RS13495Stable P2CS identifier used across views.
GenomeGCF_000450245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113131Run 6 · 1157 sequences · id 100% · cov 80%
External referencesWP_004454840.1 · A0A9Q7WRG2 · MIST4 QKC_RS13495RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QKC_RS13495
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.0000000000698:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:5.93e-25:433:100:109
  • Raw architecture: HisKA:218:0.0000000000698:278:61:64#HATPase_c:334:5.93e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450245::NZ_AVJJ01000109.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25854-27865Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKC_2694RefSeq proteinWP_004454840.1
Context group IDGCF_000450245::NZ_AVJJ01000109.1::G00043
Context members
QKC_RS13495QKC_RS13500
Partner locus tags
QKC_RS13495QKC_RS13500
Partner old locus tags
QKC_2694QKC_2695
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454840.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q7WRG2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q7WRG2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKC_RS13495Primary locus identifier stored in the genes table.
Old locus tagQKC_2694Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJJ01000109.1Sequence record reported by the local genomic context database.
Genomic interval25 854-27 164 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 854-27 865 ntGCF_000450245::NZ_AVJJ01000109.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450245::NZ_AVJJ01000109.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJJ01000109.1All displayed genes belong to this local TCS context.
Neighborhood span25 854-27 865 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 854 nt27 865 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QKC_RS13495GCF_000450245#QKC_RS13495
HKClassicCurrent focus

25 854-27 164 nt · Reverse (-)

Old locus QKC_2694RefSeq WP_004454840.1
QKC_RS13500GCF_000450245#QKC_RS13500
RROmpR

27 158-27 865 nt · Reverse (-)

Old locus QKC_2695RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113131Run 6 · HK · 1157 sequences
Representative sequenceGCF_000154625#QAB_RS0215090Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113131

Simplified PFAM architecture for HKOC_2113131

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113131
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0215090

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 335 · GCF_000450245
AssemblyASM45024v2 · Contighaploid
Genome composition4 109 406 bp · 28,5% GCClostridioides difficile DA00167
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key