Gene detail

QKC_RS08220

Histidine kinase, Classic

Clostridioides difficile DA00167 · GCF_000450245

ClassHKTypeClassicLength618 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000450245#QKC_RS08220Stable P2CS identifier used across views.
GenomeGCF_000450245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0977575Run 6 · 1368 sequences · id 100% · cov 80%
External referencesWP_003436553.1 · Q186D3 · MIST4 QKC_RS08220RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length618 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 618 aa (46.9%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa618 aa
PAS_4: 246-354 aa (109 aa)1HisKA: 363-432 aa (70 aa)2HATPase_c: 479-589 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_4#1
246-354 aa · 109 aa · 17.6% of protein
Raw tokenPAS_4:246:0.000000000208:354:115:110
2 HisKA#2
363-432 aa · 70 aa · 11.3% of protein
Raw tokenHisKA:363:0.00000000000000119:432:70:64
3 HATPase_c#3
479-589 aa · 111 aa · 18.0% of protein
Raw tokenHATPase_c:479:8.9e-28:589:111:109
  • Raw architecture: PAS_4:246:0.000000000208:354:115:110#HisKA:363:0.00000000000000119:432:70:64#HATPase_c:479:8.9e-28:589:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000450245::NZ_AVJJ01000066.1::G00024
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7754-9610Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQKC_1621RefSeq proteinWP_003436553.1
Context group IDGCF_000450245::NZ_AVJJ01000066.1::G00024
Context members
QKC_RS08220
Partner locus tags
QKC_RS08220
Partner old locus tags
QKC_1621
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003436553.1Primary protein accession used for annex mappings.
UniProt accessionQ186D3Primary UniProt accession resolved in the annex database.
UniProt IDQ186D3_CLOD6Display identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQKC_RS08220Primary locus identifier stored in the genes table.
Old locus tagQKC_1621Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJJ01000066.1Sequence record reported by the local genomic context database.
Genomic interval7 754-9 610 nt1 857 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 754-9 610 ntGCF_000450245::NZ_AVJJ01000066.1::G00024

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450245::NZ_AVJJ01000066.1::G00024

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJJ01000066.1All displayed genes belong to this local TCS context.
Neighborhood span7 754-9 610 nt1 857 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 754 nt9 610 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QKC_RS08220GCF_000450245#QKC_RS08220
HKClassicCurrent focus

7 754-9 610 nt · Forward (+)

Old locus QKC_1621RefSeq WP_003436553.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0977575Run 6 · HK · 1368 sequences
Representative sequenceGCF_000009205#CD630_RS08620Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0977575

Simplified PFAM architecture for HKOC_0977575

PFAM domain coverage: 290 / 618 aa (46.9%)

1 aa618 aa
PAS_4: 246-354 aaPAS_4HisKA: 363-432 aaHisKAHATPase_c: 479-589 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[246-354] | HisKA[363-432] | HATPase_c[479-589]
  • Domain count: 3
  • Matched identifier: HKOC_0977575
  • Positioned domains: PAS_4 246-354 ; HisKA 363-432 ; HATPase_c 479-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS08620

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 1 368 total members. Page 1 / 28.

GCF_000009205#CD630_RS08620 (representative)
CD630_RS08620 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000154625#QAB_RS0210125
QAB_RS0210125 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000235905#HMPREF9945_RS10610
HMPREF9945_RS10610 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000242355#MUI_RS0107120
MUI_RS0107120 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000376285#B131_RS0111700
B131_RS0111700 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000438845#M018_RS0108950
M018_RS0108950 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448725#QAW_RS08665
QAW_RS08665 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448745#QC1_RS08515
QC1_RS08515 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448765#QC5_RS07880
QC5_RS07880 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448805#QKI_RS08885
QKI_RS08885 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448825#QAO_RS07675
QAO_RS07675 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448845#QAQ_RS07870
QAQ_RS07870 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448865#QAS_RS08080
QAS_RS08080 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448885#QAU_RS07745
QAU_RS07745 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448905#QAY_RS07680
QAY_RS07680 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448925#QC7_RS08380
QC7_RS08380 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448965#QCA_RS08415
QCA_RS08415 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000448985#QCC_RS07325
QCC_RS07325 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449005#QCE_RS07745
QCE_RS07745 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449025#QCG_RS08810
QCG_RS08810 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449045#QCI_RS07975
QCI_RS07975 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449065#QCK_RS09920
QCK_RS09920 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449085#QCM_RS07795
QCM_RS07795 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449105#QCO_RS07695
QCO_RS07695 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449125#QCQ_RS08480
QCQ_RS08480 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449205#QMQ_RS08170
QMQ_RS08170 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449225#QCY_RS08160
QCY_RS08160 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449245#QEA_RS08420
QEA_RS08420 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449265#QMK_RS08035
QMK_RS08035 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449305#QEK_RS09005
QEK_RS09005 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449325#QEM_RS07015
QEM_RS07015 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449365#QEQ_RS08045
QEQ_RS08045 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449385#QES_RS09605
QES_RS09605 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449405#QEU_RS07565
QEU_RS07565 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449445#QEY_RS07890
QEY_RS07890 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449465#QG1_RS08910
QG1_RS08910 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449485#QG3_RS07500
QG3_RS07500 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449545#QG9_RS07780
QG9_RS07780 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449565#QMI_RS08120
QMI_RS08120 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449585#QGA_RS08665
QGA_RS08665 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449625#QMM_RS08165
QMM_RS08165 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449645#QGE_RS08790
QGE_RS08790 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449665#QGG_RS07420
QGG_RS07420 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449685#QGK_RS07620
QGK_RS07620 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449705#QGM_RS07995
QGM_RS07995 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449725#QGO_RS07145
QGO_RS07145 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449745#QGQ_RS10235
QGQ_RS10235 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449785#QGW_RS08380
QGW_RS08380 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449805#QGY_RS07770
QGY_RS07770 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3
GCF_000449825#QI3_RS08280
QI3_RS08280 · HK · Classic
RefSeq: WP_003436553.1
UniProt: Q186D3

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 335 · GCF_000450245
AssemblyASM45024v2 · Contighaploid
Genome composition4 109 406 bp · 28,5% GCClostridioides difficile DA00167
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key