1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw token
HisKA:245:0.00000000000198:309:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QK7_RS00105
Histidine kinase, Classic
Clostridioides difficile DA00154 · GCF_000450185
ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450185#QK7_RS00105Stable P2CS identifier used across views.
GenomeGCF_000450185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw token
HATPase_c:357:6.03e-18:466:110:109- Raw architecture: HisKA:245:0.00000000000198:309:65:64#HATPase_c:357:6.03e-18:466:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000450185::NZ_AVJG01000004.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2458-4616Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQK7_3848RefSeq proteinWP_021378163.1
Context group ID
GCF_000450185::NZ_AVJG01000004.1::G00001Context members
QK7_RS00100QK7_RS00105
Partner locus tags
QK7_RS00100QK7_RS00105
Partner old locus tags
QK7_3847QK7_3848
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021378163.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3EI62Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3EI62_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQK7_RS00105Primary locus identifier stored in the genes table.
Old locus tagQK7_3848Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJG01000004.1Sequence record reported by the local genomic context database.
Genomic interval3 210-4 616 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 458-4 616 ntGCF_000450185::NZ_AVJG01000004.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000450185::NZ_AVJG01000004.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJG01000004.1All displayed genes belong to this local TCS context.
Neighborhood span2 458-4 616 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 458 nt4 616 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QK7_RS00100GCF_000450185#QK7_RS00100
RROmpR
2 458-3 165 nt · Forward (+)
QK7_RS00105GCF_000450185#QK7_RS00105
HKClassicCurrent focus
3 210-4 616 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000235905#HMPREF9945_RS05015Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1737766
Simplified PFAM architecture for HKOC_1737766
PFAM domain coverage: 175 / 468 aa (37.4%)
1 aa468 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-310] | HATPase_c[358-466]
- Domain count: 2
- Matched identifier: HKOC_1737766
- Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Representative gene: GCF_000235905#HMPREF9945_RS05015
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 332 · GCF_000450185
AssemblyASM45018v2 · Contighaploid
Genome composition4 126 663 bp · 28,5% GCClostridioides difficile DA00154
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key