Gene detail

QK3_RS08935

Histidine kinase, Classic

Clostridioides difficile DA00145 · GCF_000450145

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450145#QK3_RS08935Stable P2CS identifier used across views.
GenomeGCF_000450145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1748394Run 6 · 17 sequences · id 100% · cov 80% · representative
External referencesWP_021396918.1 · MIST4 QK3_RS08935RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.00000455:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000148:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.19e-26:465:108:109
  • Raw architecture: HAMP:166:0.00000455:232:69:69#HisKA:245:0.0000000000000148:312:68:64#HATPase_c:359:1.19e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450145::NZ_AVJE01000071.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4027-6159Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQK3_1800RefSeq proteinWP_021396918.1
Context group IDGCF_000450145::NZ_AVJE01000071.1::G00026
Context members
QK3_RS08930QK3_RS08935
Partner locus tags
QK3_RS08930QK3_RS08935
Partner old locus tags
QK3_1799QK3_1800
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021396918.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQK3_RS08935Primary locus identifier stored in the genes table.
Old locus tagQK3_1800Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVJE01000071.1Sequence record reported by the local genomic context database.
Genomic interval4 756-6 159 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 027-6 159 ntGCF_000450145::NZ_AVJE01000071.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450145::NZ_AVJE01000071.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVJE01000071.1All displayed genes belong to this local TCS context.
Neighborhood span4 027-6 159 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 027 nt6 159 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QK3_RS08930GCF_000450145#QK3_RS08930
RROmpR

4 027-4 752 nt · Forward (+)

Old locus QK3_1799RefSeq WP_009893221.1
QK3_RS08935GCF_000450145#QK3_RS08935
HKClassicCurrent focus

4 756-6 159 nt · Forward (+)

Old locus QK3_1800RefSeq WP_021396918.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748394Run 6 · HK · 17 sequences
Representative sequenceGCF_000450145#QK3_RS08935The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748394

Simplified PFAM architecture for HKOC_1748394

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1748394
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS08935

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 17 over 17 total members. Page 1 / 1.

GCF_000450145#QK3_RS08935 (representative)
QK3_RS08935 · HK · Classic
RefSeq: WP_021396918.1
GCF_000452005#QUI_RS10275
QUI_RS10275 · HK · Classic
RefSeq: WP_021396918.1
GCF_000530295#BN174_RS08285
BN174_RS08285 · HK · Classic
RefSeq: WP_021396918.1
GCF_000531255#BN173_RS08295
BN173_RS08295 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114315#FLH66_RS12650
FLH66_RS12650 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114485#FLH54_RS12645
FLH54_RS12645 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114515#FLH53_RS12685
FLH53_RS12685 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114585#FLH52_RS10225
FLH52_RS10225 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114605#FLH51_RS13745
FLH51_RS13745 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114885#FLH88_RS12355
FLH88_RS12355 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114905#FLH87_RS13235
FLH87_RS13235 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114915#FLH60_RS13405
FLH60_RS13405 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114935#FLH82_RS14685
FLH82_RS14685 · HK · Classic
RefSeq: WP_021396918.1
GCF_007114945#FLH71_RS13670
FLH71_RS13670 · HK · Classic
RefSeq: WP_021396918.1
GCF_036699155#LFB10_RS08065
LFB10_RS08065 · HK · Classic
RefSeq: WP_021396918.1
GCF_900243205#DBQ24_RS17430
DBQ24_RS17430 · HK · Classic
RefSeq: WP_021396918.1
GCF_900243345#DBQ31_RS01840
DBQ31_RS01840 · HK · Classic
RefSeq: WP_021396918.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 330 · GCF_000450145
AssemblyASM45014v2 · Contighaploid
Genome composition4 051 066 bp · 28,5% GCClostridioides difficile DA00145
Signal transduction countsGenes 101 · HK 47 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key