Gene detail

QIS_RS04870

Histidine kinase, Classic

Clostridioides difficile DA00131 · GCF_000450045

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450045#QIS_RS04870Stable P2CS identifier used across views.
GenomeGCF_000450045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876517Run 6 · 193 sequences · id 100% · cov 80%
External referencesWP_022620459.1 · MIST4 QIS_RS04870RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QIS_RS04870
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000119:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:6.26e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000119:156:63:64#HATPase_c:204:6.26e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450045::NZ_AVIZ01000053.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span38243-39867Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIS_0818RefSeq proteinWP_022620459.1
Context group IDGCF_000450045::NZ_AVIZ01000053.1::G00017
Context members
QIS_RS04865QIS_RS04870
Partner locus tags
QIS_RS04865QIS_RS04870
Partner old locus tags
QIS_0817QIS_0818
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022620459.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQIS_RS04870Primary locus identifier stored in the genes table.
Old locus tagQIS_0818Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIZ01000053.1Sequence record reported by the local genomic context database.
Genomic interval38 932-39 867 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span38 243-39 867 ntGCF_000450045::NZ_AVIZ01000053.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450045::NZ_AVIZ01000053.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIZ01000053.1All displayed genes belong to this local TCS context.
Neighborhood span38 243-39 867 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
38 243 nt39 867 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QIS_RS04865GCF_000450045#QIS_RS04865
RROmpR

38 243-38 935 nt · Forward (+)

Old locus QIS_0817RefSeq WP_009888625.1
QIS_RS04870GCF_000450045#QIS_RS04870
HKClassicCurrent focus

38 932-39 867 nt · Forward (+)

Old locus QIS_0818RefSeq WP_022620459.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876517Run 6 · HK · 193 sequences
Representative sequenceGCF_000448745#QC1_RS05145Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876517

Simplified PFAM architecture for HKOC_2876517

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876517
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS05145

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 325 · GCF_000450045
AssemblyASM45004v2 · Contighaploid
Genome composition4 080 324 bp · 28,5% GCClostridioides difficile DA00131
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key