Gene detail

QIG_RS02300

Histidine kinase, Classic

Clostridioides difficile DA00065 · GCF_000449945

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449945#QIG_RS02300Stable P2CS identifier used across views.
GenomeGCF_000449945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557694Run 6 · 240 sequences · id 100% · cov 80%
External referencesWP_003426348.1 · A0A9P4D9Z5 · MIST4 QIG_RS02300RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000682:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000612:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.93e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000682:152:70:69#HisKA:164:0.0000000612:217:54:64#HATPase_c:278:1.93e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449945::NZ_AVIU01000017.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span58399-60221Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIG_0463RefSeq proteinWP_003426348.1
Context group IDGCF_000449945::NZ_AVIU01000017.1::G00005
Context members
QIG_RS02300QIG_RS02305
Partner locus tags
QIG_RS02300QIG_RS02305
Partner old locus tags
QIG_0463QIG_0464
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426348.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4D9Z5Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4D9Z5_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQIG_RS02300Primary locus identifier stored in the genes table.
Old locus tagQIG_0463Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIU01000017.1Sequence record reported by the local genomic context database.
Genomic interval58 399-59 559 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span58 399-60 221 ntGCF_000449945::NZ_AVIU01000017.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449945::NZ_AVIU01000017.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIU01000017.1All displayed genes belong to this local TCS context.
Neighborhood span58 399-60 221 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
58 399 nt60 221 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QIG_RS02300GCF_000449945#QIG_RS02300
HKClassicCurrent focus

58 399-59 559 nt · Reverse (-)

Old locus QIG_0463RefSeq WP_003426348.1
QIG_RS02305GCF_000449945#QIG_RS02305
RROmpR

59 547-60 221 nt · Reverse (-)

Old locus QIG_0464RefSeq WP_003426350.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557694Run 6 · HK · 240 sequences
Representative sequenceGCF_000210395#CDM68_RS02700Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557694

Simplified PFAM architecture for HKOC_2557694

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557694
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS02700

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 240 total members. Page 1 / 5.

GCF_000210395#CDM68_RS02700 (representative)
CDM68_RS02700 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000210415#CDCF5_RS02755
CDCF5_RS02755 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000235825#HMPREF1122_RS15475
HMPREF1122_RS15475 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000235925#HMPREF1123_RS13730
HMPREF1123_RS13730 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000449945#QIG_RS02300
QIG_RS02300 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000452125#QUY_RS02385
QUY_RS02385 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000452165#QW3_RS09595
QW3_RS09595 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000530915#BN167_RS02715
BN167_RS02715 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_000531625#BN168_RS02715
BN168_RS02715 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_001971875#BER36_RS03135
BER36_RS03135 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_001972195#BER37_RS02935
BER37_RS02935 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002301085#BGU06_RS16320
BGU06_RS16320 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002301435#BGU22_RS10845
BGU22_RS10845 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002301555#BGU29_RS15760
BGU29_RS15760 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002301635#BGU36_RS09135
BGU36_RS09135 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002302945#BGV12_RS01440
BGV12_RS01440 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002303045#BGV18_RS14505
BGV18_RS14505 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002303155#BGV23_RS16225
BGV23_RS16225 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002303485#BGU64_RS01775
BGU64_RS01775 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002303545#BGU67_RS14820
BGU67_RS14820 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_002940825#AWN77_RS01930
AWN77_RS01930 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003095675#DDG63_RS03110
DDG63_RS03110 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003095695#DDG61_RS03325
DDG61_RS03325 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003324025#DVA88_RS16045
DVA88_RS16045 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003324035#DVA87_RS12885
DVA87_RS12885 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326835#DVA92_RS15115
DVA92_RS15115 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326845#DVA91_RS13320
DVA91_RS13320 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326875#DVA94_RS14760
DVA94_RS14760 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326885#DVA93_RS15890
DVA93_RS15890 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326915#DVA96_RS13155
DVA96_RS13155 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326935#DVA97_RS14525
DVA97_RS14525 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326945#DVA98_RS07650
DVA98_RS07650 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326965#DVA99_RS01505
DVA99_RS01505 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003326985#DVB00_RS13390
DVB00_RS13390 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327015#DVB04_RS12325
DVB04_RS12325 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327025#DVB06_RS12625
DVB06_RS12625 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327055#DVB02_RS08945
DVB02_RS08945 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327065#DVB01_RS00065
DVB01_RS00065 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327105#DVB12_RS05735
DVB12_RS05735 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327115#DVB09_RS14760
DVB09_RS14760 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327145#DVB10_RS13905
DVB10_RS13905 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327165#DVB07_RS12625
DVB07_RS12625 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327185#DVB14_RS06100
DVB14_RS06100 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327205#DVB16_RS08675
DVB16_RS08675 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327215#DVB15_RS11805
DVB15_RS11805 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327245#DVB19_RS06995
DVB19_RS06995 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327265#DVB18_RS16045
DVB18_RS16045 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327325#DVB05_RS09945
DVB05_RS09945 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327345#DVB13_RS10160
DVB13_RS10160 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5
GCF_003327365#DVB11_RS08835
DVB11_RS08835 · HK · Classic
RefSeq: WP_003426348.1
UniProt: A0A9P4D9Z5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 319 · GCF_000449945
AssemblyASM44994v2 · Contighaploid
Genome composition4 138 699 bp · 28,5% GCClostridioides difficile DA00065
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key