1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw token
H_kinase_N:12:1.53e-36:142:132:139P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QIE_RS09780
Histidine kinase, Classic
Clostridioides difficile DA00062 · GCF_000449925
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449925#QIE_RS09780Stable P2CS identifier used across views.
GenomeGCF_000449925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw token
HisKA_2:276:2.46e-16:350:76:763 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw token
HATPase_c:370:0.0000000689:467:114:109- Raw architecture: H_kinase_N:12:1.53e-36:142:132:139#HisKA_2:276:2.46e-16:350:76:76#HATPase_c:370:0.0000000689:467:114:109
- Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449925::NZ_AVIT01000085.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17707-19684Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIE_1977RefSeq proteinWP_003435429.1
Context group ID
GCF_000449925::NZ_AVIT01000085.1::G00033Context members
QIE_RS09775QIE_RS09780
Partner locus tags
QIE_RS09775QIE_RS09780
Partner old locus tags
QIE_1976QIE_1977
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003435429.1Primary protein accession used for annex mappings.
UniProt accessionQ187M1Primary UniProt accession resolved in the annex database.
UniProt IDQ187M1_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQIE_RS09780Primary locus identifier stored in the genes table.
Old locus tagQIE_1977Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIT01000085.1Sequence record reported by the local genomic context database.
Genomic interval18 275-19 684 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 707-19 684 ntGCF_000449925::NZ_AVIT01000085.1::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449925::NZ_AVIT01000085.1::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIT01000085.1All displayed genes belong to this local TCS context.
Neighborhood span17 707-19 684 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 707 nt19 684 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QIE_RS09775GCF_000449925#QIE_RS09775
RRAmiR_NasR
17 707-18 282 nt · Forward (+)
QIE_RS09780GCF_000449925#QIE_RS09780
HKClassicCurrent focus
18 275-19 684 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_041537345#ACD536_RS00630Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0878348
Simplified PFAM architecture for HKOC_0878348
PFAM domain coverage: 466 / 658 aa (70.8%)
1 aa658 aa
Response_regANTARGAF_PdtaSHisKA_2HATPase_c
- Simplified architecture: Response_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c
- Raw architecture: Response_reg[5-115] | ANTAR[134-186] | GAF_PdtaS[195-330] | HisKA_2[465-536] | HATPase_c[562-655]
- Domain count: 5
- Matched identifier: HKOC_0878348
- Positioned domains: Response_reg 5-115 ; ANTAR 134-186 ; GAF_PdtaS 195-330 ; HisKA_2 465-536 ; HATPase_c 562-655
Cluster members and taxonomy
Representative gene: GCF_041537345#ACD536_RS00630
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 318 · GCF_000449925
AssemblyASM44992v2 · Contighaploid
Genome composition4 066 705 bp · 28,5% GCClostridioides difficile DA00062
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key