Gene detail

QGW_RS08865

Histidine kinase, Classic

Clostridioides difficile 824 · GCF_000449785

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449785#QGW_RS08865Stable P2CS identifier used across views.
GenomeGCF_000449785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1748392Run 6 · 30 sequences · id 100% · cov 80%
External referencesWP_021371203.1 · MIST4 QGW_RS08865RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.0000207:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000136:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.2e-26:465:108:109
  • Raw architecture: HAMP:166:0.0000207:232:69:69#HisKA:245:0.0000000000000136:312:68:64#HATPase_c:359:1.2e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449785::NZ_AVIM01000060.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span124214-126346Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGW_1791RefSeq proteinWP_021371203.1
Context group IDGCF_000449785::NZ_AVIM01000060.1::G00028
Context members
QGW_RS08860QGW_RS08865
Partner locus tags
QGW_RS08860QGW_RS08865
Partner old locus tags
QGW_1790QGW_1791
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021371203.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGW_RS08865Primary locus identifier stored in the genes table.
Old locus tagQGW_1791Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIM01000060.1Sequence record reported by the local genomic context database.
Genomic interval124 943-126 346 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span124 214-126 346 ntGCF_000449785::NZ_AVIM01000060.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449785::NZ_AVIM01000060.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIM01000060.1All displayed genes belong to this local TCS context.
Neighborhood span124 214-126 346 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
124 214 nt126 346 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGW_RS08860GCF_000449785#QGW_RS08860
RROmpR

124 214-124 939 nt · Forward (+)

Old locus QGW_1790RefSeq WP_004454491.1
QGW_RS08865GCF_000449785#QGW_RS08865
HKClassicCurrent focus

124 943-126 346 nt · Forward (+)

Old locus QGW_1791RefSeq WP_021371203.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748392Run 6 · HK · 30 sequences
Representative sequenceGCF_000449045#QCI_RS08455Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748392

Simplified PFAM architecture for HKOC_1748392

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1748392
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449045#QCI_RS08455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 309 · GCF_000449785
AssemblyASM44978v2 · Contighaploid
Genome composition4 185 643 bp · 28,5% GCClostridioides difficile 824
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key