Gene detail

QGW_RS02465

Histidine kinase, Classic

Clostridioides difficile 824 · GCF_000449785

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449785#QGW_RS02465Stable P2CS identifier used across views.
GenomeGCF_000449785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557914Run 6 · 27 sequences · id 100% · cov 80%
External referencesWP_021370922.1 · MIST4 QGW_RS02465RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000781:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000596:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.98e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000781:152:70:69#HisKA:164:0.0000000596:217:54:64#HATPase_c:278:1.98e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449785::NZ_AVIM01000017.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span69477-71299Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGW_0489RefSeq proteinWP_021370922.1
Context group IDGCF_000449785::NZ_AVIM01000017.1::G00007
Context members
QGW_RS02465QGW_RS02470
Partner locus tags
QGW_RS02465QGW_RS02470
Partner old locus tags
QGW_0489QGW_0490
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021370922.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGW_RS02465Primary locus identifier stored in the genes table.
Old locus tagQGW_0489Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIM01000017.1Sequence record reported by the local genomic context database.
Genomic interval69 477-70 637 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span69 477-71 299 ntGCF_000449785::NZ_AVIM01000017.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449785::NZ_AVIM01000017.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIM01000017.1All displayed genes belong to this local TCS context.
Neighborhood span69 477-71 299 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
69 477 nt71 299 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGW_RS02465GCF_000449785#QGW_RS02465
HKClassicCurrent focus

69 477-70 637 nt · Reverse (-)

Old locus QGW_0489RefSeq WP_021370922.1
QGW_RS02470GCF_000449785#QGW_RS02470
RROmpR

70 625-71 299 nt · Reverse (-)

Old locus QGW_0490RefSeq WP_021363249.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557914Run 6 · HK · 27 sequences
Representative sequenceGCF_000449045#QCI_RS02685Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557914

Simplified PFAM architecture for HKOC_2557914

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557914
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449045#QCI_RS02685

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 27 over 27 total members. Page 1 / 1.

GCF_000449045#QCI_RS02685 (representative)
QCI_RS02685 · HK · Classic
RefSeq: WP_021370922.1
GCF_000449785#QGW_RS02465
QGW_RS02465 · HK · Classic
RefSeq: WP_021370922.1
GCF_000632735#BG47_RS03820
BG47_RS03820 · HK · Classic
RefSeq: WP_021370922.1
GCF_003482065#CDIF28666_RS03300
CDIF28666_RS03300 · HK · Classic
RefSeq: WP_021370922.1
GCF_003862975#EGL86_RS16045
EGL86_RS16045 · HK · Classic
RefSeq: WP_021370922.1
GCF_004317645#E0Q60_RS02500
E0Q60_RS02500 · HK · Classic
RefSeq: WP_021370922.1
GCF_004318405#E0R07_RS00710
E0R07_RS00710 · HK · Classic
RefSeq: WP_021370922.1
GCF_004318425#E0Q86_RS09070
E0Q86_RS09070 · HK · Classic
RefSeq: WP_021370922.1
GCF_007114815#FLH90_RS17150
FLH90_RS17150 · HK · Classic
RefSeq: WP_021370922.1
GCF_007114825#FLH89_RS16785
FLH89_RS16785 · HK · Classic
RefSeq: WP_021370922.1
GCF_007114835#FLH39_RS16790
FLH39_RS16790 · HK · Classic
RefSeq: WP_021370922.1
GCF_025532375#H3T49_RS16585
H3T49_RS16585 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533315#H3U39_RS16565
H3U39_RS16565 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533375#H3U37_RS08910
H3U37_RS08910 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533715#H3U59_RS11605
H3U59_RS11605 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533795#H3U65_RS11560
H3U65_RS11560 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533815#H3U70_RS11565
H3U70_RS11565 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533875#H3U67_RS11570
H3U67_RS11570 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533905#H3U60_RS11545
H3U60_RS11545 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533935#H3U71_RS11560
H3U71_RS11560 · HK · Classic
RefSeq: WP_021370922.1
GCF_025533955#H3U68_RS11530
H3U68_RS11530 · HK · Classic
RefSeq: WP_021370922.1
GCF_036699055#LFA99_RS15385
LFA99_RS15385 · HK · Classic
RefSeq: WP_021370922.1
GCF_900164295#B2B14_RS14495
B2B14_RS14495 · HK · Classic
RefSeq: WP_021370922.1
GCF_900164455#B2B47_RS14280
B2B47_RS14280 · HK · Classic
RefSeq: WP_021370922.1
GCF_900165065#B2C25_RS14765
B2C25_RS14765 · HK · Classic
RefSeq: WP_021370922.1
GCF_900165455#B2A60_RS17495
B2A60_RS17495 · HK · Classic
RefSeq: WP_021370922.1
GCF_900165575#B2B39_RS12980
B2B39_RS12980 · HK · Classic
RefSeq: WP_021370922.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 309 · GCF_000449785
AssemblyASM44978v2 · Contighaploid
Genome composition4 185 643 bp · 28,5% GCClostridioides difficile 824
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key