Gene detail

QGO_RS02390

Histidine kinase, Classic

Clostridioides difficile CD212 · GCF_000449725

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449725#QGO_RS02390Stable P2CS identifier used across views.
GenomeGCF_000449725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557704Run 6 · 179 sequences · id 100% · cov 80%
External referencesWP_003434762.1 · A0A6N3EY34 · MIST4 QGO_RS02390RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000695:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000641:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.17e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000695:152:70:69#HisKA:164:0.0000000641:217:54:64#HATPase_c:278:1.17e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449725::NZ_AVIJ01000009.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span135921-137743Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGO_0478RefSeq proteinWP_003434762.1
Context group IDGCF_000449725::NZ_AVIJ01000009.1::G00006
Context members
QGO_RS02390QGO_RS02395
Partner locus tags
QGO_RS02390QGO_RS02395
Partner old locus tags
QGO_0478QGO_0479
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434762.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3EY34Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3EY34_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGO_RS02390Primary locus identifier stored in the genes table.
Old locus tagQGO_0478Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIJ01000009.1Sequence record reported by the local genomic context database.
Genomic interval135 921-137 081 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span135 921-137 743 ntGCF_000449725::NZ_AVIJ01000009.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449725::NZ_AVIJ01000009.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIJ01000009.1All displayed genes belong to this local TCS context.
Neighborhood span135 921-137 743 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
135 921 nt137 743 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGO_RS02390GCF_000449725#QGO_RS02390
HKClassicCurrent focus

135 921-137 081 nt · Reverse (-)

Old locus QGO_0478RefSeq WP_003434762.1
QGO_RS02395GCF_000449725#QGO_RS02395
RROmpR

137 069-137 743 nt · Reverse (-)

Old locus QGO_0479RefSeq WP_003434773.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557704Run 6 · HK · 179 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS15250Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557704

Simplified PFAM architecture for HKOC_2557704

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557704
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS15250

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 179 total members. Page 1 / 4.

GCF_000235905#HMPREF9945_RS15250 (representative)
HMPREF9945_RS15250 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000448985#QCC_RS02345
QCC_RS02345 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000449665#QGG_RS02160
QGG_RS02160 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000449685#QGK_RS02440
QGK_RS02440 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000449725#QGO_RS02390
QGO_RS02390 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000451245#QE9_RS02290
QE9_RS02290 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000531295#BN190_RS02485
BN190_RS02485 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_000531535#BN187_RS02775
BN187_RS02775 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_001971945#BER41_RS02760
BER41_RS02760 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_001972085#BER42_RS02815
BER42_RS02815 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002007885#BZ168_RS15750
BZ168_RS15750 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002234355#CGC51_RS02810
CGC51_RS02810 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002300835#BGT93_RS03210
BGT93_RS03210 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002300925#BGT98_RS08140
BGT98_RS08140 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301025#BGU04_RS17785
BGU04_RS17785 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301125#BGU09_RS15775
BGU09_RS15775 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301245#BGU14_RS17810
BGU14_RS17810 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301305#BGU25_RS03190
BGU25_RS03190 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301325#BGU32_RS00425
BGU32_RS00425 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301335#BGU33_RS10715
BGU33_RS10715 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301375#BGU35_RS15265
BGU35_RS15265 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301575#BGU30_RS02445
BGU30_RS02445 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301655#BGU37_RS13385
BGU37_RS13385 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301675#BGU38_RS14585
BGU38_RS14585 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301765#BGU41_RS06400
BGU41_RS06400 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002301805#BGU43_RS12780
BGU43_RS12780 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302005#BGU83_RS13915
BGU83_RS13915 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302125#BGU89_RS06150
BGU89_RS06150 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302225#BGU97_RS04510
BGU97_RS04510 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302245#BGU99_RS12995
BGU99_RS12995 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302265#BGU76_RS07490
BGU76_RS07490 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302305#BGU78_RS12865
BGU78_RS12865 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302465#BGU79_RS09800
BGU79_RS09800 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002302925#BGV11_RS05055
BGV11_RS05055 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002303025#BGV17_RS01365
BGV17_RS01365 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002303245#BGU57_RS07815
BGU57_RS07815 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002303325#BGU54_RS15850
BGU54_RS15850 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002303345#BGU55_RS16200
BGU55_RS16200 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002303715#BGU75_RS12760
BGU75_RS12760 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002304245#BGU98_RS14565
BGU98_RS14565 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002304255#BGU94_RS15600
BGU94_RS15600 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_002812605#CWR56_RS02240
CWR56_RS02240 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003862635#EGM10_RS12605
EGM10_RS12605 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003862765#EGM00_RS17815
EGM00_RS17815 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003862865#EGL96_RS08745
EGL96_RS08745 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003863045#EGL81_RS15360
EGL81_RS15360 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003863235#EGL92_RS14115
EGL92_RS14115 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_003863265#EGL85_RS15330
EGL85_RS15330 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_004317745#E0Q70_RS04015
E0Q70_RS04015 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34
GCF_004317985#E0Q71_RS14205
E0Q71_RS14205 · HK · Classic
RefSeq: WP_003434762.1
UniProt: A0A6N3EY34

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 305 · GCF_000449725
AssemblyASM44972v2 · Contighaploid
Genome composition4 003 929 bp · 28,5% GCClostridioides difficile CD212
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key