Gene detail

QGE_RS04260

Histidine kinase, Classic

Clostridioides difficile CD200 · GCF_000449645

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449645#QGE_RS04260Stable P2CS identifier used across views.
GenomeGCF_000449645Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1738099Run 6 · 158 sequences · id 100% · cov 80%
External referencesWP_021367592.1 · MIST4 QGE_RS04260RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QGE_RS04260
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.00000000000219:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:9.73e-18:466:111:109
  • Raw architecture: HisKA:245:0.00000000000219:309:65:64#HATPase_c:357:9.73e-18:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449645::NZ_AVIF01000072.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2738-4896Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGE_0652RefSeq proteinWP_021367592.1
Context group IDGCF_000449645::NZ_AVIF01000072.1::G00013
Context members
QGE_RS04255QGE_RS04260
Partner locus tags
QGE_RS04255QGE_RS04260
Partner old locus tags
QGE_0651QGE_0652
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021367592.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGE_RS04260Primary locus identifier stored in the genes table.
Old locus tagQGE_0652Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIF01000072.1Sequence record reported by the local genomic context database.
Genomic interval3 490-4 896 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 738-4 896 ntGCF_000449645::NZ_AVIF01000072.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449645::NZ_AVIF01000072.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIF01000072.1All displayed genes belong to this local TCS context.
Neighborhood span2 738-4 896 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 738 nt4 896 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGE_RS04255GCF_000449645#QGE_RS04255
RROmpR

2 738-3 445 nt · Forward (+)

Old locus QGE_0651RefSeq WP_009888460.1
QGE_RS04260GCF_000449645#QGE_RS04260
HKClassicCurrent focus

3 490-4 896 nt · Forward (+)

Old locus QGE_0652RefSeq WP_021367592.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1738099Run 6 · HK · 158 sequences
Representative sequenceGCF_000448805#QKI_RS03780Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1738099

Simplified PFAM architecture for HKOC_1738099

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1738099
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS03780

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 300 · GCF_000449645
AssemblyASM44964v2 · Contighaploid
Genome composition4 296 879 bp · 28,0% GCClostridioides difficile CD200
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key