Gene detail

QGA_RS14220

Histidine kinase, Classic

Clostridioides difficile CD181 · GCF_000449585

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449585#QGA_RS14220Stable P2CS identifier used across views.
GenomeGCF_000449585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0598844Run 6 · 163 sequences · id 100% · cov 80%
External referencesWP_022618542.1 · MIST4 QGA_RS14220RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QGA_RS14220
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.69e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000364:775:110:109
  • Raw architecture: HisKA:558:1.69e-18:624:67:64#HATPase_c:671:0.000000000364:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449585::NZ_AVID01000070.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9656-12680Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGA_2912RefSeq proteinWP_022618542.1
Context group IDGCF_000449585::NZ_AVID01000070.1::G00043
Context members
QGA_RS14220QGA_RS14225
Partner locus tags
QGA_RS14220QGA_RS14225
Partner old locus tags
QGA_2912QGA_2913
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022618542.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGA_RS14220Primary locus identifier stored in the genes table.
Old locus tagQGA_2912Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVID01000070.1Sequence record reported by the local genomic context database.
Genomic interval9 656-11 992 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 656-12 680 ntGCF_000449585::NZ_AVID01000070.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449585::NZ_AVID01000070.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVID01000070.1All displayed genes belong to this local TCS context.
Neighborhood span9 656-12 680 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 656 nt12 680 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGA_RS14220GCF_000449585#QGA_RS14220
HKClassicCurrent focus

9 656-11 992 nt · Reverse (-)

Old locus QGA_2912RefSeq WP_022618542.1
QGA_RS14225GCF_000449585#QGA_RS14225
RROmpR

11 964-12 680 nt · Reverse (-)

Old locus QGA_2913RefSeq WP_003431132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0598844Run 6 · HK · 163 sequences
Representative sequenceGCF_000154625#QAB_RS0215275Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0598844

Simplified PFAM architecture for HKOC_0598844

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0598844
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0215275

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 299 · GCF_000449585
AssemblyASM44958v2 · Contighaploid
Genome composition4 338 534 bp · 28,5% GCClostridioides difficile CD181
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key