Gene detail

QG3_RS10135

Histidine kinase, Classic

Clostridioides difficile CD169 · GCF_000449485

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449485#QG3_RS10135Stable P2CS identifier used across views.
GenomeGCF_000449485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2180370Run 6 · 101 sequences · id 100% · cov 80%
External referencesWP_016728477.1 · MIST4 QG3_RS10135RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 429 aa (79.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QG3_RS10135
Domain-by-domain annotation4 items
1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw tokenHAMP:6:0.000000849:74:69:69
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw tokenPAS_9:96:0.00000124:195:103:102
3 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw tokenHisKA:202:3.14e-18:268:67:64
4 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw tokenHATPase_c:319:3.66e-30:422:104:109
  • Raw architecture: HAMP:6:0.000000849:74:69:69#PAS_9:96:0.00000124:195:103:102#HisKA:202:3.14e-18:268:67:64#HATPase_c:319:3.66e-30:422:104:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449485::NZ_AVHZ01000027.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span395360-397370Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQG3_2056RefSeq proteinWP_016728477.1
Context group IDGCF_000449485::NZ_AVHZ01000027.1::G00039
Context members
QG3_RS10135QG3_RS10140
Partner locus tags
QG3_RS10135QG3_RS10140
Partner old locus tags
QG3_2056QG3_2057
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728477.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQG3_RS10135Primary locus identifier stored in the genes table.
Old locus tagQG3_2056Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHZ01000027.1Sequence record reported by the local genomic context database.
Genomic interval395 360-396 649 nt1 290 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span395 360-397 370 ntGCF_000449485::NZ_AVHZ01000027.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449485::NZ_AVHZ01000027.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHZ01000027.1All displayed genes belong to this local TCS context.
Neighborhood span395 360-397 370 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
395 360 nt397 370 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QG3_RS10135GCF_000449485#QG3_RS10135
HKClassicCurrent focus

395 360-396 649 nt · Reverse (-)

Old locus QG3_2056RefSeq WP_016728477.1
QG3_RS10140GCF_000449485#QG3_RS10140
RROmpR

396 678-397 370 nt · Reverse (-)

Old locus QG3_2057RefSeq WP_003416112.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2180370Run 6 · HK · 101 sequences
Representative sequenceGCF_000242355#MUI_RS0100685Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2180370

Simplified PFAM architecture for HKOC_2180370

PFAM domain coverage: 321 / 429 aa (74.8%)

1 aa429 aa
HAMP: 33-74 aaHAMPPAS: 87-193 aaPASHisKA: 202-267 aaHisKAHATPase_c: 317-422 aaHATPase_c
HAMPPASHisKAHATPase_c
  • Simplified architecture: HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: HAMP[33-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
  • Domain count: 4
  • Matched identifier: HKOC_2180370
  • Positioned domains: HAMP 33-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0100685

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 295 · GCF_000449485
AssemblyASM44948v2 · Contighaploid
Genome composition4 009 115 bp · 28,5% GCClostridioides difficile CD169
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key