Gene detail

QEY_RS03220

Histidine kinase, Classic

Clostridioides difficile CD165 · GCF_000449445

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449445#QEY_RS03220Stable P2CS identifier used across views.
GenomeGCF_000449445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882092Run 6 · 169 sequences · id 100% · cov 80%
External referencesWP_021366243.1 · A0A069A5W9 · MIST4 QEY_RS03220RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
HisKA: 85-154 aa (70 aa)1HATPase_c: 201-304 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw tokenHisKA:85:0.00000000000163:154:70:64
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw tokenHATPase_c:201:5.74e-28:304:106:109
  • Raw architecture: HisKA:85:0.00000000000163:154:70:64#HATPase_c:201:5.74e-28:304:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449445::NZ_AVHX01000023.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15207-16813Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEY_0642RefSeq proteinWP_021366243.1
Context group IDGCF_000449445::NZ_AVHX01000023.1::G00011
Context members
QEY_RS03215QEY_RS03220
Partner locus tags
QEY_RS03215QEY_RS03220
Partner old locus tags
QEY_0641QEY_0642
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366243.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A5W9Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A5W9_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEY_RS03220Primary locus identifier stored in the genes table.
Old locus tagQEY_0642Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHX01000023.1Sequence record reported by the local genomic context database.
Genomic interval15 896-16 813 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 207-16 813 ntGCF_000449445::NZ_AVHX01000023.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449445::NZ_AVHX01000023.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHX01000023.1All displayed genes belong to this local TCS context.
Neighborhood span15 207-16 813 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 207 nt16 813 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEY_RS03215GCF_000449445#QEY_RS03215
RROmpR

15 207-15 896 nt · Forward (+)

Old locus QEY_0641RefSeq WP_016729263.1
QEY_RS03220GCF_000449445#QEY_RS03220
HKClassicCurrent focus

15 896-16 813 nt · Forward (+)

Old locus QEY_0642RefSeq WP_021366243.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882092Run 6 · HK · 169 sequences
Representative sequenceGCF_000448765#QC5_RS03005Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882092

Simplified PFAM architecture for HKOC_2882092

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 88-154 aaHisKAHATPase_c: 201-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-154] | HATPase_c[201-304]
  • Domain count: 2
  • Matched identifier: HKOC_2882092
  • Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS03005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 293 · GCF_000449445
AssemblyASM44944v2 · Contighaploid
Genome composition4 086 646 bp · 28,5% GCClostridioides difficile CD165
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key