Gene detail

QEQ_RS20080

Histidine kinase, Classic

Clostridioides difficile CD144 · GCF_000449365

ClassHKTypeClassicLength260 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449365#QEQ_RS20080Stable P2CS identifier used across views.
GenomeGCF_000449365Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293545Run 6 · 574 sequences · id 100% · cov 80%
External referencesWP_234779638.1 · MIST4 QEQ_RS20080RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length260 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 260 aa (64.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEQ_RS20080
Domain-by-domain annotation2 items
1 HisKA#1
42-101 aa · 60 aa · 23.1% of protein
Raw tokenHisKA:42:0.0000000012:101:60:64
2 HATPase_c#2
147-253 aa · 107 aa · 41.2% of protein
Raw tokenHATPase_c:147:1.87e-22:253:107:109
  • Raw architecture: HisKA:42:0.0000000012:101:60:64#HATPase_c:147:1.87e-22:253:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449365::NZ_AVHT01000029.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span171141-173075Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEQ_1482RefSeq proteinWP_234779638.1
Context group IDGCF_000449365::NZ_AVHT01000029.1::G00021
Context members
QEQ_RS07400QEQ_RS20080
Partner locus tags
QEQ_RS07400QEQ_RS20080
Partner old locus tags
QEQ_1480QEQ_1482
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_234779638.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEQ_RS20080Primary locus identifier stored in the genes table.
Old locus tagQEQ_1482Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHT01000029.1Sequence record reported by the local genomic context database.
Genomic interval172 293-173 075 nt783 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span171 141-173 075 ntGCF_000449365::NZ_AVHT01000029.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449365::NZ_AVHT01000029.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHT01000029.1All displayed genes belong to this local TCS context.
Neighborhood span171 141-173 075 nt1 935 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
171 141 nt173 075 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEQ_RS07400GCF_000449365#QEQ_RS07400
RROmpR

171 141-171 845 nt · Forward (+)

Old locus QEQ_1480RefSeq WP_011861224.1
QEQ_RS20080GCF_000449365#QEQ_RS20080
HKClassicCurrent focus

172 293-173 075 nt · Forward (+)

Old locus QEQ_1482RefSeq WP_234779638.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293545Run 6 · HK · 574 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS05765Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293545

Simplified PFAM architecture for HKOC_2293545

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293545
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS05765

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 289 · GCF_000449365
AssemblyASM44936v2 · Contighaploid
Genome composition4 095 302 bp · 28,5% GCClostridioides difficile CD144
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key