Gene detail

QEQ_RS03635

Histidine kinase, Classic

Clostridioides difficile CD144 · GCF_000449365

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449365#QEQ_RS03635Stable P2CS identifier used across views.
GenomeGCF_000449365Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1738098Run 6 · 276 sequences · id 100% · cov 80%
External referencesWP_021364310.1 · A0A9X8WPV4 · MIST4 QEQ_RS03635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEQ_RS03635
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.0000000000019:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:9.2e-18:466:111:109
  • Raw architecture: HisKA:245:0.0000000000019:309:65:64#HATPase_c:357:9.2e-18:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449365::NZ_AVHT01000018.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span79361-81519Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEQ_0699RefSeq proteinWP_021364310.1
Context group IDGCF_000449365::NZ_AVHT01000018.1::G00014
Context members
QEQ_RS03630QEQ_RS03635
Partner locus tags
QEQ_RS03630QEQ_RS03635
Partner old locus tags
QEQ_0698QEQ_0699
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364310.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8WPV4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8WPV4_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEQ_RS03635Primary locus identifier stored in the genes table.
Old locus tagQEQ_0699Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHT01000018.1Sequence record reported by the local genomic context database.
Genomic interval80 113-81 519 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span79 361-81 519 ntGCF_000449365::NZ_AVHT01000018.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449365::NZ_AVHT01000018.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHT01000018.1All displayed genes belong to this local TCS context.
Neighborhood span79 361-81 519 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
79 361 nt81 519 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEQ_RS03630GCF_000449365#QEQ_RS03630
RROmpR

79 361-80 068 nt · Forward (+)

Old locus QEQ_0698RefSeq WP_009888460.1
QEQ_RS03635GCF_000449365#QEQ_RS03635
HKClassicCurrent focus

80 113-81 519 nt · Forward (+)

Old locus QEQ_0699RefSeq WP_021364310.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1738098Run 6 · HK · 276 sequences
Representative sequenceGCF_000448745#QC1_RS04415Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1738098

Simplified PFAM architecture for HKOC_1738098

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1738098
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS04415

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 289 · GCF_000449365
AssemblyASM44936v2 · Contighaploid
Genome composition4 095 302 bp · 28,5% GCClostridioides difficile CD144
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key