Gene detail

QEO_RS02445

Histidine kinase, Classic

Clostridioides difficile CD133 · GCF_000449345

ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449345#QEO_RS02445Stable P2CS identifier used across views.
GenomeGCF_000449345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2880543Run 6 · 850 sequences · id 100% · cov 80%
External referencesWP_003434209.1 · A0AB74QD71 · MIST4 QEO_RS02445RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
HisKA: 89-151 aa (63 aa)1HATPase_c: 199-306 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw tokenHisKA:89:0.0000000525:151:63:64
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw tokenHATPase_c:199:1.07e-29:306:108:109
  • Raw architecture: HisKA:89:0.0000000525:151:63:64#HATPase_c:199:1.07e-29:306:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449345::NZ_AVHS01000016.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4290-5916Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEO_0455RefSeq proteinWP_003434209.1
Context group IDGCF_000449345::NZ_AVHS01000016.1::G00003
Context members
QEO_RS02445QEO_RS02450
Partner locus tags
QEO_RS02445QEO_RS02450
Partner old locus tags
QEO_0455QEO_0456
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434209.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QD71Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QD71_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEO_RS02445Primary locus identifier stored in the genes table.
Old locus tagQEO_0455Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHS01000016.1Sequence record reported by the local genomic context database.
Genomic interval4 290-5 213 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 290-5 916 ntGCF_000449345::NZ_AVHS01000016.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449345::NZ_AVHS01000016.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHS01000016.1All displayed genes belong to this local TCS context.
Neighborhood span4 290-5 916 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 290 nt5 916 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEO_RS02445GCF_000449345#QEO_RS02445
HKClassicCurrent focus

4 290-5 213 nt · Reverse (-)

Old locus QEO_0455RefSeq WP_003434209.1
QEO_RS02450GCF_000449345#QEO_RS02450
RROmpR

5 215-5 916 nt · Reverse (-)

Old locus QEO_0456RefSeq WP_009895385.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2880543Run 6 · HK · 850 sequences
Representative sequenceGCF_000154625#QAB_RS0204060Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2880543

Simplified PFAM architecture for HKOC_2880543

PFAM domain coverage: 172 / 307 aa (56.0%)

1 aa307 aa
HisKA: 88-151 aaHisKAHATPase_c: 199-306 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-151] | HATPase_c[199-306]
  • Domain count: 2
  • Matched identifier: HKOC_2880543
  • Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0204060

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 850 total members. Page 1 / 17.

GCF_000154625#QAB_RS0204060 (representative)
QAB_RS0204060 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000155025#UAB_RS0202875
UAB_RS0202875 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000235905#HMPREF9945_RS16435
HMPREF9945_RS16435 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000242355#MUI_RS0107555
MUI_RS0107555 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000376285#B131_RS0101330
B131_RS0101330 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000438845#M018_RS0119515
M018_RS0119515 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000448725#QAW_RS01750
QAW_RS01750 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000448845#QAQ_RS01680
QAQ_RS01680 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000448865#QAS_RS01880
QAS_RS01880 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000448965#QCA_RS01720
QCA_RS01720 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000448985#QCC_RS01780
QCC_RS01780 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449085#QCM_RS01680
QCM_RS01680 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449105#QCO_RS02430
QCO_RS02430 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449145#QCS_RS01675
QCS_RS01675 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449165#QCU_RS01720
QCU_RS01720 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449265#QMK_RS01880
QMK_RS01880 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449345#QEO_RS02445
QEO_RS02445 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449485#QG3_RS00560
QG3_RS00560 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449505#QG5_RS03140
QG5_RS03140 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449545#QG9_RS01915
QG9_RS01915 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449585#QGA_RS02475
QGA_RS02475 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449665#QGG_RS04640
QGG_RS04640 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449685#QGK_RS01835
QGK_RS01835 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449725#QGO_RS01825
QGO_RS01825 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449745#QGQ_RS15900
QGQ_RS15900 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449765#QGU_RS02240
QGU_RS02240 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449845#QI5_RS01530
QI5_RS01530 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449865#QI7_RS11540
QI7_RS11540 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000449885#QIA_RS02765
QIA_RS02765 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450005#QIM_RS01980
QIM_RS01980 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450065#QIU_RS02200
QIU_RS02200 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450085#QIW_RS02260
QIW_RS02260 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450105#QIY_RS01990
QIY_RS01990 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450125#QK1_RS16285
QK1_RS16285 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450245#QKC_RS02245
QKC_RS02245 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450305#QKK_RS02240
QKK_RS02240 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450345#QKO_RS02185
QKO_RS02185 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450385#QKS_RS01975
QKS_RS01975 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450465#QM1_RS01605
QM1_RS01605 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450485#QM3_RS01780
QM3_RS01780 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450545#QM9_RS01725
QM9_RS01725 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450565#QMA_RS02080
QMA_RS02080 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450605#QME_RS02360
QME_RS02360 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450625#QQS_RS02215
QQS_RS02215 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450665#QMS_RS01885
QMS_RS01885 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450825#QOG_RS01675
QOG_RS01675 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450865#QOK_RS01785
QOK_RS01785 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450885#QOM_RS01620
QOM_RS01620 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450925#QQK_RS01715
QQK_RS01715 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71
GCF_000450965#QQQ_RS01805
QQQ_RS01805 · HK · Classic
RefSeq: WP_003434209.1
UniProt: A0AB74QD71

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 288 · GCF_000449345
AssemblyASM44934v2 · Contighaploid
Genome composition4 107 124 bp · 28,0% GCClostridioides difficile CD133
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key