Gene detail

QEM_RS11815

Histidine kinase, Classic

Clostridioides difficile CD132 · GCF_000449325

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449325#QEM_RS11815Stable P2CS identifier used across views.
GenomeGCF_000449325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113477Run 6 · 25 sequences · id 100% · cov 80%
External referencesWP_021369672.1 · MIST4 QEM_RS11815RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEM_RS11815
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.0000000000701:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:7.35e-25:433:100:109
  • Raw architecture: HisKA:218:0.0000000000701:278:61:64#HATPase_c:334:7.35e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449325::NZ_AVHR01000126.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7396-9407Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEM_2398RefSeq proteinWP_021369672.1
Context group IDGCF_000449325::NZ_AVHR01000126.1::G00035
Context members
QEM_RS11815QEM_RS11820
Partner locus tags
QEM_RS11815QEM_RS11820
Partner old locus tags
QEM_2398QEM_2399
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021369672.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEM_RS11815Primary locus identifier stored in the genes table.
Old locus tagQEM_2398Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHR01000126.1Sequence record reported by the local genomic context database.
Genomic interval7 396-8 706 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 396-9 407 ntGCF_000449325::NZ_AVHR01000126.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449325::NZ_AVHR01000126.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHR01000126.1All displayed genes belong to this local TCS context.
Neighborhood span7 396-9 407 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 396 nt9 407 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEM_RS11815GCF_000449325#QEM_RS11815
HKClassicCurrent focus

7 396-8 706 nt · Reverse (-)

Old locus QEM_2398RefSeq WP_021369672.1
QEM_RS11820GCF_000449325#QEM_RS11820
RROmpR

8 700-9 407 nt · Reverse (-)

Old locus QEM_2399RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113477Run 6 · HK · 25 sequences
Representative sequenceGCF_000449005#QCE_RS12945Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113477

Simplified PFAM architecture for HKOC_2113477

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113477
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449005#QCE_RS12945

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 287 · GCF_000449325
AssemblyASM44932v2 · Contighaploid
Genome composition3 956 938 bp · 28,5% GCClostridioides difficile CD132
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key