Gene detail

QEM_RS08960

Histidine kinase, Classic

Clostridioides difficile CD132 · GCF_000449325

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449325#QEM_RS08960Stable P2CS identifier used across views.
GenomeGCF_000449325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2884663Run 6 · 606 sequences · id 100% · cov 80%
External referencesWP_009897088.1 · Q187R5 · MIST4 QEM_RS08960RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 196-295 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.0000000826:144:63:64
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw tokenHATPase_c:196:2.39e-22:295:100:109
  • Raw architecture: HisKA:82:0.0000000826:144:63:64#HATPase_c:196:2.39e-22:295:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449325::NZ_AVHR01000101.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span45260-46841Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEM_1821RefSeq proteinWP_009897088.1
Context group IDGCF_000449325::NZ_AVHR01000101.1::G00030
Context members
QEM_RS08960QEM_RS08965
Partner locus tags
QEM_RS08960QEM_RS08965
Partner old locus tags
QEM_1821QEM_1822
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009897088.1Primary protein accession used for annex mappings.
UniProt accessionQ187R5Primary UniProt accession resolved in the annex database.
UniProt IDQ187R5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEM_RS08960Primary locus identifier stored in the genes table.
Old locus tagQEM_1821Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHR01000101.1Sequence record reported by the local genomic context database.
Genomic interval45 260-46 168 nt909 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span45 260-46 841 ntGCF_000449325::NZ_AVHR01000101.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449325::NZ_AVHR01000101.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHR01000101.1All displayed genes belong to this local TCS context.
Neighborhood span45 260-46 841 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
45 260 nt46 841 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEM_RS08960GCF_000449325#QEM_RS08960
HKClassicCurrent focus

45 260-46 168 nt · Reverse (-)

Old locus QEM_1821RefSeq WP_009897088.1
QEM_RS08965GCF_000449325#QEM_RS08965
RROmpR

46 170-46 841 nt · Reverse (-)

Old locus QEM_1822RefSeq WP_009897090.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2884663Run 6 · HK · 606 sequences
Representative sequenceGCF_000009205#CD630_RS10595Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2884663

Simplified PFAM architecture for HKOC_2884663

PFAM domain coverage: 165 / 302 aa (54.6%)

1 aa302 aa
HisKA: 82-144 aaHisKAHATPase_c: 195-296 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[82-144] | HATPase_c[195-296]
  • Domain count: 2
  • Matched identifier: HKOC_2884663
  • Positioned domains: HisKA 82-144 ; HATPase_c 195-296
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS10595

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 287 · GCF_000449325
AssemblyASM44932v2 · Contighaploid
Genome composition3 956 938 bp · 28,5% GCClostridioides difficile CD132
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key