Gene detail

QEM_RS02000

Histidine kinase, Classic

Clostridioides difficile CD132 · GCF_000449325

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449325#QEM_RS02000Stable P2CS identifier used across views.
GenomeGCF_000449325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503579Run 6 · 56 sequences · id 100% · cov 80%
External referencesWP_021361762.1 · MIST4 QEM_RS02000RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QEM_RS02000
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000088:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:3.43e-19:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000088:240:59:64#HATPase_c:293:3.43e-19:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449325::NZ_AVHR01000030.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11859-13702Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEM_0407RefSeq proteinWP_021361762.1
Context group IDGCF_000449325::NZ_AVHR01000030.1::G00003
Context members
QEM_RS02000QEM_RS02005
Partner locus tags
QEM_RS02000QEM_RS02005
Partner old locus tags
QEM_0407QEM_0408
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021361762.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQEM_RS02000Primary locus identifier stored in the genes table.
Old locus tagQEM_0407Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHR01000030.1Sequence record reported by the local genomic context database.
Genomic interval11 859-13 040 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 859-13 702 ntGCF_000449325::NZ_AVHR01000030.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449325::NZ_AVHR01000030.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHR01000030.1All displayed genes belong to this local TCS context.
Neighborhood span11 859-13 702 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 859 nt13 702 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QEM_RS02000GCF_000449325#QEM_RS02000
HKClassicCurrent focus

11 859-13 040 nt · Reverse (-)

Old locus QEM_0407RefSeq WP_021361762.1
QEM_RS02005GCF_000449325#QEM_RS02005
RROmpR

13 040-13 702 nt · Reverse (-)

Old locus QEM_0408RefSeq WP_003434705.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503579Run 6 · HK · 56 sequences
Representative sequenceGCF_000448885#QAU_RS02345Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503579

Simplified PFAM architecture for HKOC_2503579

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503579
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448885#QAU_RS02345

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 287 · GCF_000449325
AssemblyASM44932v2 · Contighaploid
Genome composition3 956 938 bp · 28,5% GCClostridioides difficile CD132
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key