1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw token
HisKA:89:0.0000000525:151:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QMK_RS01880
Histidine kinase, Classic
Clostridioides difficile DA00273 · GCF_000449265
ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449265#QMK_RS01880Stable P2CS identifier used across views.
GenomeGCF_000449265Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw token
HATPase_c:199:1.07e-29:306:108:109- Raw architecture: HisKA:89:0.0000000525:151:63:64#HATPase_c:199:1.07e-29:306:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449265::NZ_AVKF01000029.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4397-6023Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQMK_0342RefSeq proteinWP_003434209.1
Context group ID
GCF_000449265::NZ_AVKF01000029.1::G00002Context members
QMK_RS01880QMK_RS01885
Partner locus tags
QMK_RS01880QMK_RS01885
Partner old locus tags
QMK_0342QMK_0343
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434209.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QD71Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QD71_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQMK_RS01880Primary locus identifier stored in the genes table.
Old locus tagQMK_0342Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKF01000029.1Sequence record reported by the local genomic context database.
Genomic interval4 397-5 320 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 397-6 023 ntGCF_000449265::NZ_AVKF01000029.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449265::NZ_AVKF01000029.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKF01000029.1All displayed genes belong to this local TCS context.
Neighborhood span4 397-6 023 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 397 nt6 023 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QMK_RS01880GCF_000449265#QMK_RS01880
HKClassicCurrent focus
4 397-5 320 nt · Reverse (-)
QMK_RS01885GCF_000449265#QMK_RS01885
RROmpR
5 322-6 023 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000154625#QAB_RS0204060Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2880543
Simplified PFAM architecture for HKOC_2880543
PFAM domain coverage: 172 / 307 aa (56.0%)
1 aa307 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-151] | HATPase_c[199-306]
- Domain count: 2
- Matched identifier: HKOC_2880543
- Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Representative gene: GCF_000154625#QAB_RS0204060
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 357 · GCF_000449265
AssemblyASM44926v2 · Contighaploid
Genome composition4 095 984 bp · 28,5% GCClostridioides difficile DA00273
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key