1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw token
HisKA:168:0.000000000000404:234:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QEA_RS18495
Histidine kinase, Classic
Clostridioides difficile CD109 · GCF_000449245
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449245#QEA_RS18495Stable P2CS identifier used across views.
GenomeGCF_000449245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw token
HATPase_c:280:1.06e-26:388:110:109- Raw architecture: HisKA:168:0.000000000000404:234:67:64#HATPase_c:280:1.06e-26:388:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449245::NZ_AVHL01000128.1::G00055
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11057-12920Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQEA_3748RefSeq proteinWP_022618228.1
Context group ID
GCF_000449245::NZ_AVHL01000128.1::G00055Context members
QEA_RS18495QEA_RS18500
Partner locus tags
QEA_RS18495QEA_RS18500
Partner old locus tags
QEA_3748QEA_3749
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_022618228.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q7ZZ38Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q7ZZ38_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQEA_RS18495Primary locus identifier stored in the genes table.
Old locus tagQEA_3748Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHL01000128.1Sequence record reported by the local genomic context database.
Genomic interval11 057-12 238 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 057-12 920 ntGCF_000449245::NZ_AVHL01000128.1::G00055
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449245::NZ_AVHL01000128.1::G00055Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHL01000128.1All displayed genes belong to this local TCS context.
Neighborhood span11 057-12 920 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 057 nt12 920 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QEA_RS18495GCF_000449245#QEA_RS18495
HKClassicCurrent focus
11 057-12 238 nt · Reverse (-)
QEA_RS18500GCF_000449245#QEA_RS18500
RROmpR
12 228-12 920 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448725#QAW_RS18635Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503572
Simplified PFAM architecture for HKOC_2503572
PFAM domain coverage: 175 / 393 aa (44.5%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[168-233] | HATPase_c[281-389]
- Domain count: 2
- Matched identifier: HKOC_2503572
- Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Representative gene: GCF_000448725#QAW_RS18635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 281 · GCF_000449245
AssemblyASM44924v2 · Contighaploid
Genome composition4 109 854 bp · 28,5% GCClostridioides difficile CD109
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key