Gene detail

QMQ_RS13325

Histidine kinase, Classic

Clostridioides difficile DA00306 · GCF_000449205

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449205#QMQ_RS13325Stable P2CS identifier used across views.
GenomeGCF_000449205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440525Run 6 · 1678 sequences · id 100% · cov 80%
External referencesWP_004454923.1 · Q182U1 · MIST4 QMQ_RS13325RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.78e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.0000000015:400:108:109
  • Raw architecture: His_kinase:205:2.78e-31:283:80:80#HATPase_c:300:0.0000000015:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449205::NZ_AVKI01000047.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span54451-56428Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQMQ_2702RefSeq proteinWP_004454923.1
Context group IDGCF_000449205::NZ_AVKI01000047.1::G00043
Context members
QMQ_RS13320QMQ_RS13325
Partner locus tags
QMQ_RS13320QMQ_RS13325
Partner old locus tags
QMQ_2701QMQ_2702
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454923.1Primary protein accession used for annex mappings.
UniProt accessionQ182U1Primary UniProt accession resolved in the annex database.
UniProt IDQ182U1_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQMQ_RS13325Primary locus identifier stored in the genes table.
Old locus tagQMQ_2702Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKI01000047.1Sequence record reported by the local genomic context database.
Genomic interval55 226-56 428 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span54 451-56 428 ntGCF_000449205::NZ_AVKI01000047.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449205::NZ_AVKI01000047.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKI01000047.1All displayed genes belong to this local TCS context.
Neighborhood span54 451-56 428 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
54 451 nt56 428 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QMQ_RS13320GCF_000449205#QMQ_RS13320
RRLytTR

54 451-55 221 nt · Reverse (-)

Old locus QMQ_2701RefSeq WP_004454921.1
QMQ_RS13325GCF_000449205#QMQ_RS13325
HKClassicCurrent focus

55 226-56 428 nt · Reverse (-)

Old locus QMQ_2702RefSeq WP_004454923.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440525Run 6 · HK · 1678 sequences
Representative sequenceGCF_000009205#CD630_RS13950Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440525

Simplified PFAM architecture for HKOC_2440525

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440525
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS13950

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 1 678 total members. Page 1 / 34.

GCF_000009205#CD630_RS13950 (representative)
CD630_RS13950 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000154625#QAB_RS0215440
QAB_RS0215440 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000155025#UAB_RS0214310
UAB_RS0214310 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000235905#HMPREF9945_RS00600
HMPREF9945_RS00600 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000376285#B131_RS0119330
B131_RS0119330 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000438845#M018_RS0102745
M018_RS0102745 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448725#QAW_RS13850
QAW_RS13850 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448745#QC1_RS13730
QC1_RS13730 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448805#QKI_RS14165
QKI_RS14165 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448825#QAO_RS12855
QAO_RS12855 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448845#QAQ_RS12905
QAQ_RS12905 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448865#QAS_RS13405
QAS_RS13405 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448885#QAU_RS13320
QAU_RS13320 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448905#QAY_RS12815
QAY_RS12815 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448925#QC7_RS13640
QC7_RS13640 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448965#QCA_RS13700
QCA_RS13700 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000448985#QCC_RS12780
QCC_RS12780 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449005#QCE_RS13315
QCE_RS13315 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449025#QCG_RS13835
QCG_RS13835 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449045#QCI_RS13155
QCI_RS13155 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449065#QCK_RS15055
QCK_RS15055 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449085#QCM_RS12920
QCM_RS12920 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449105#QCO_RS13565
QCO_RS13565 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449125#QCQ_RS13645
QCQ_RS13645 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449145#QCS_RS12840
QCS_RS12840 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449165#QCU_RS12825
QCU_RS12825 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449205#QMQ_RS13325
QMQ_RS13325 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449225#QCY_RS13325
QCY_RS13325 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449245#QEA_RS13675
QEA_RS13675 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449265#QMK_RS13360
QMK_RS13360 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449305#QEK_RS14035
QEK_RS14035 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449325#QEM_RS12155
QEM_RS12155 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449345#QEO_RS13410
QEO_RS13410 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449365#QEQ_RS13480
QEQ_RS13480 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449385#QES_RS14665
QES_RS14665 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449405#QEU_RS12930
QEU_RS12930 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449445#QEY_RS13080
QEY_RS13080 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449465#QG1_RS14560
QG1_RS14560 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449505#QG5_RS14150
QG5_RS14150 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449565#QMI_RS13330
QMI_RS13330 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449585#QGA_RS14385
QGA_RS14385 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449625#QMM_RS13405
QMM_RS13405 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449645#QGE_RS13850
QGE_RS13850 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449665#QGG_RS12825
QGG_RS12825 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449685#QGK_RS12915
QGK_RS12915 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449725#QGO_RS12810
QGO_RS12810 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449765#QGU_RS13620
QGU_RS13620 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449785#QGW_RS13340
QGW_RS13340 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449805#QGY_RS12935
QGY_RS12935 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1
GCF_000449825#QI3_RS13370
QI3_RS13370 · HK · Classic
RefSeq: WP_004454923.1
UniProt: Q182U1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 360 · GCF_000449205
AssemblyASM44920v2 · Contighaploid
Genome composition4 080 248 bp · 28,5% GCClostridioides difficile DA00306
Signal transduction countsGenes 99 · HK 46 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key