1 HAMP#1
172-215 aa · 44 aa · 9.4% of protein
Raw token
HAMP:172:0.0000106:215:44:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCW_RS15805
Histidine kinase, Classic
Clostridioides difficile CD69 · GCF_000449185
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449185#QCW_RS15805Stable P2CS identifier used across views.
GenomeGCF_000449185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage209 / 469 aa (44.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 HisKA#2
250-308 aa · 59 aa · 12.6% of protein
Raw token
HisKA:250:0.0000000000000648:308:59:643 HATPase_c#3
364-469 aa · 106 aa · 22.6% of protein
Raw token
HATPase_c:364:1.21e-25:469:107:109- Raw architecture: HAMP:172:0.0000106:215:44:69#HisKA:250:0.0000000000000648:308:59:64#HATPase_c:364:1.21e-25:469:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449185::NZ_AVHE01000049.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span75761-77892Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCW_3268RefSeq proteinWP_021376387.1
Context group ID
GCF_000449185::NZ_AVHE01000049.1::G00044Context members
QCW_RS15805QCW_RS15810
Partner locus tags
QCW_RS15805QCW_RS15810
Partner old locus tags
QCW_3268QCW_3269
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021376387.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCW_RS15805Primary locus identifier stored in the genes table.
Old locus tagQCW_3268Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHE01000049.1Sequence record reported by the local genomic context database.
Genomic interval75 761-77 170 nt1 410 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span75 761-77 892 ntGCF_000449185::NZ_AVHE01000049.1::G00044
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449185::NZ_AVHE01000049.1::G00044Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHE01000049.1All displayed genes belong to this local TCS context.
Neighborhood span75 761-77 892 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 761 nt77 892 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCW_RS15805GCF_000449185#QCW_RS15805
HKClassicCurrent focus
75 761-77 170 nt · Reverse (-)
QCW_RS15810GCF_000449185#QCW_RS15810
RROmpR
77 176-77 892 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449185#QCW_RS15805The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1727353
Simplified PFAM architecture for HKOC_1727353
PFAM domain coverage: 163 / 469 aa (34.8%)
1 aa469 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[251-308] | HATPase_c[364-468]
- Domain count: 2
- Matched identifier: HKOC_1727353
- Positioned domains: HisKA 251-308 ; HATPase_c 364-468
Cluster members and taxonomy
Representative gene: GCF_000449185#QCW_RS15805
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 274 · GCF_000449185
AssemblyASM44918v2 · Contighaploid
Genome composition3 991 067 bp · 28,5% GCClostridioides difficile CD69
Signal transduction countsGenes 95 · HK 43 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key