Gene detail

QCW_RS08520

Histidine kinase, Classic

Clostridioides difficile CD69 · GCF_000449185

ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449185#QCW_RS08520Stable P2CS identifier used across views.
GenomeGCF_000449185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2354502Run 6 · 39 sequences · id 100% · cov 80% · representative
External referencesWP_032547396.1 · MIST4 QCW_RS08520RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCW_RS08520
Domain-by-domain annotation2 items
1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw tokenHisKA:185:0.000000000179:250:66:64
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw tokenHATPase_c:296:7.31e-25:408:113:109
  • Raw architecture: HisKA:185:0.000000000179:250:66:64#HATPase_c:296:7.31e-25:408:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449185::NZ_AVHE01000033.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span79069-80962Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCW_1757RefSeq proteinWP_032547396.1
Context group IDGCF_000449185::NZ_AVHE01000033.1::G00023
Context members
QCW_RS08515QCW_RS08520
Partner locus tags
QCW_RS08515QCW_RS08520
Partner old locus tags
QCW_1756QCW_1757
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032547396.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCW_RS08520Primary locus identifier stored in the genes table.
Old locus tagQCW_1757Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHE01000033.1Sequence record reported by the local genomic context database.
Genomic interval79 730-80 962 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span79 069-80 962 ntGCF_000449185::NZ_AVHE01000033.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449185::NZ_AVHE01000033.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHE01000033.1All displayed genes belong to this local TCS context.
Neighborhood span79 069-80 962 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
79 069 nt80 962 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCW_RS08515GCF_000449185#QCW_RS08515
RROmpR

79 069-79 740 nt · Forward (+)

Old locus QCW_1756RefSeq WP_009889581.1
QCW_RS08520GCF_000449185#QCW_RS08520
HKClassicCurrent focus

79 730-80 962 nt · Forward (+)

Old locus QCW_1757RefSeq WP_032547396.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2354502Run 6 · HK · 39 sequences
Representative sequenceGCF_000449185#QCW_RS08520The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2354502

Simplified PFAM architecture for HKOC_2354502

PFAM domain coverage: 178 / 410 aa (43.4%)

1 aa410 aa
HisKA: 185-250 aaHisKAHATPase_c: 297-408 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[185-250] | HATPase_c[297-408]
  • Domain count: 2
  • Matched identifier: HKOC_2354502
  • Positioned domains: HisKA 185-250 ; HATPase_c 297-408
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS08520

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 274 · GCF_000449185
AssemblyASM44918v2 · Contighaploid
Genome composition3 991 067 bp · 28,5% GCClostridioides difficile CD69
Signal transduction countsGenes 95 · HK 43 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key