Gene detail

QCU_RS02425

Histidine kinase, Classic

Clostridioides difficile CD68 · GCF_000449165

ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449165#QCU_RS02425Stable P2CS identifier used across views.
GenomeGCF_000449165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338482Run 6 · 2212 sequences · id 100% · cov 80%
External referencesWP_003439079.1 · A0A0H3MZ77 · MIST4 QCU_RS02425RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCU_RS02425
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw tokenHisKA:304:0.00000000000013:371:68:64
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw tokenHATPase_c:416:2.53e-31:525:110:109
  • Raw architecture: HisKA:304:0.00000000000013:371:68:64#HATPase_c:416:2.53e-31:525:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449165::NZ_AVHD01000031.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22111-24413Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCU_0467RefSeq proteinWP_003439079.1
Context group IDGCF_000449165::NZ_AVHD01000031.1::G00008
Context members
QCU_RS02425QCU_RS02430
Partner locus tags
QCU_RS02425QCU_RS02430
Partner old locus tags
QCU_0467QCU_0468
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003439079.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ77Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ77_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCU_RS02425Primary locus identifier stored in the genes table.
Old locus tagQCU_0467Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHD01000031.1Sequence record reported by the local genomic context database.
Genomic interval22 111-23 718 nt1 608 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span22 111-24 413 ntGCF_000449165::NZ_AVHD01000031.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449165::NZ_AVHD01000031.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHD01000031.1All displayed genes belong to this local TCS context.
Neighborhood span22 111-24 413 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 111 nt24 413 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCU_RS02425GCF_000449165#QCU_RS02425
HKClassicCurrent focus

22 111-23 718 nt · Forward (+)

Old locus QCU_0467RefSeq WP_003439079.1
QCU_RS02430GCF_000449165#QCU_RS02430
RROmpR

23 709-24 413 nt · Forward (+)

Old locus QCU_0468RefSeq WP_003439080.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338482Run 6 · HK · 2212 sequences
Representative sequenceGCF_000003215#QAC_RS0202670Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338482

Simplified PFAM architecture for HKOC_1338482

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338482
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202670

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 2 212 total members. Page 1 / 45.

GCF_000003215#QAC_RS0202670 (representative)
QAC_RS0202670 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000009205#CD630_RS03175
CD630_RS03175 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000027105#CDR20291_RS02715
CDR20291_RS02715 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000085225#CD196_RS02830
CD196_RS02830 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000154625#QAB_RS0204725
QAB_RS0204725 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000154685#AEC_RS0204145
AEC_RS0204145 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000155025#UAB_RS0203680
UAB_RS0203680 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000210455#CD7855_RS02705
CD7855_RS02705 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000211235#CDBI1_RS02805
CDBI1_RS02805 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000235905#HMPREF9945_RS05255
HMPREF9945_RS05255 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000242355#MUI_RS0102425
MUI_RS0102425 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000376285#B131_RS0102875
B131_RS0102875 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000438845#M018_RS0112750
M018_RS0112750 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448725#QAW_RS02500
QAW_RS02500 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448745#QC1_RS03635
QC1_RS03635 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448805#QKI_RS03015
QKI_RS03015 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448825#QAO_RS02435
QAO_RS02435 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448845#QAQ_RS02425
QAQ_RS02425 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448865#QAS_RS02500
QAS_RS02500 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448885#QAU_RS02560
QAU_RS02560 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448905#QAY_RS02510
QAY_RS02510 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448925#QC7_RS02840
QC7_RS02840 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448965#QCA_RS02440
QCA_RS02440 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000448985#QCC_RS02480
QCC_RS02480 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449005#QCE_RS02430
QCE_RS02430 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449025#QCG_RS03015
QCG_RS03015 · HK · Classic
RefSeq: WP_021370071.1
GCF_000449045#QCI_RS02825
QCI_RS02825 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449065#QCK_RS04170
QCK_RS04170 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449085#QCM_RS02310
QCM_RS02310 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449105#QCO_RS02540
QCO_RS02540 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449125#QCQ_RS03150
QCQ_RS03150 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449145#QCS_RS02345
QCS_RS02345 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449165#QCU_RS02425
QCU_RS02425 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449205#QMQ_RS02695
QMQ_RS02695 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449225#QCY_RS02920
QCY_RS02920 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449245#QEA_RS02880
QEA_RS02880 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449265#QMK_RS02240
QMK_RS02240 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449305#QEK_RS03345
QEK_RS03345 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449325#QEM_RS02225
QEM_RS02225 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449345#QEO_RS03145
QEO_RS03145 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449365#QEQ_RS02865
QEQ_RS02865 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449385#QES_RS03775
QES_RS03775 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449405#QEU_RS02435
QEU_RS02435 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449445#QEY_RS02245
QEY_RS02245 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449465#QG1_RS03665
QG1_RS03665 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449485#QG3_RS02325
QG3_RS02325 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449505#QG5_RS03780
QG5_RS03780 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449545#QG9_RS02595
QG9_RS02595 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449565#QMI_RS02795
QMI_RS02795 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77
GCF_000449585#QGA_RS03145
QGA_RS03145 · HK · Classic
RefSeq: WP_003439079.1
UniProt: A0A0H3MZ77

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 273 · GCF_000449165
AssemblyASM44916v2 · Contighaploid
Genome composition3 975 975 bp · 28,0% GCClostridioides difficile CD68
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key