Gene detail

QCS_RS19660

Histidine kinase, Classic

Clostridioides difficile CD51 · GCF_000449145

ClassHKTypeClassicLength225 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000449145#QCS_RS19660Stable P2CS identifier used across views.
GenomeGCF_000449145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2054262Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_234779520.1 · MIST4 QCS_RS19660RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length225 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 225 aa (67.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa225 aa
HisKA: 18-76 aa (59 aa)1HATPase_c: 133-224 aa (92 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
18-76 aa · 59 aa · 26.2% of protein
Raw tokenHisKA:18:0.000000000216:76:59:64
2 HATPase_c#2
133-224 aa · 92 aa · 40.9% of protein
Raw tokenHATPase_c:133:0.00000000622:224:108:109
  • Raw architecture: HisKA:18:0.000000000216:76:59:64#HATPase_c:133:0.00000000622:224:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000449145::NZ_AVHC01000093.1::G00044
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span3647-4324Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCS_2746RefSeq proteinWP_234779520.1
Context group IDGCF_000449145::NZ_AVHC01000093.1::G00044
Context members
QCS_RS19660
Partner locus tags
QCS_RS19660
Partner old locus tags
QCS_2746
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_234779520.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCS_RS19660Primary locus identifier stored in the genes table.
Old locus tagQCS_2746Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHC01000093.1Sequence record reported by the local genomic context database.
Genomic interval3 647-4 324 nt678 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 647-4 324 ntGCF_000449145::NZ_AVHC01000093.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449145::NZ_AVHC01000093.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHC01000093.1All displayed genes belong to this local TCS context.
Neighborhood span3 647-4 324 nt678 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 647 nt4 324 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QCS_RS19660GCF_000449145#QCS_RS19660
HKClassicCurrent focus

3 647-4 324 nt · Reverse (-)

Old locus QCS_2746RefSeq WP_234779520.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2054262Run 6 · HK · 4 sequences
Representative sequenceGCF_004314205#E0N89_RS05980Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2054262

Simplified PFAM architecture for HKOC_2054262

PFAM domain coverage: 169 / 442 aa (38.2%)

1 aa442 aa
HAMP: 179-223 aaHAMPHisKA: 237-293 aaHisKAHATPase_c_5: 372-438 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[179-223] | HisKA[237-293] | HATPase_c_5[372-438]
  • Domain count: 3
  • Matched identifier: HKOC_2054262
  • Positioned domains: HAMP 179-223 ; HisKA 237-293 ; HATPase_c_5 372-438
Cluster members and taxonomy
Visualization

Representative gene: GCF_004314205#E0N89_RS05980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 272 · GCF_000449145
AssemblyASM44914v2 · Contighaploid
Genome composition4 011 592 bp · 28,0% GCClostridioides difficile CD51
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key