Gene detail

QCS_RS12505

Response regulator OmpR family

Clostridioides difficile CD51 · GCF_000449145

ClassRRTypeOmpRLength235 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449145#QCS_RS12505Stable P2CS identifier used across views.
GenomeGCF_000449145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1016365Run 7 · 2196 sequences · id 100% · cov 80%
External referencesWP_009890737.1 · A0A069B0L7 · MIST4 QCS_RS12505RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length235 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage187 / 235 aa (79.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCS_RS12505
Domain-by-domain annotation2 items
1 Response_reg#1
4-113 aa · 110 aa · 46.8% of protein
Raw tokenResponse_reg:4:3.42e-28:113:111:111
2 Trans_reg_C#2
151-227 aa · 77 aa · 32.8% of protein
Raw tokenTrans_reg_C:151:5.52e-32:227:77:77
  • Raw architecture: Response_reg:4:3.42e-28:113:111:111#Trans_reg_C:151:5.52e-32:227:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449145::NZ_AVHC01000088.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25839-27850Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCS_2552RefSeq proteinWP_009890737.1
Context group IDGCF_000449145::NZ_AVHC01000088.1::G00039
Context members
QCS_RS12500QCS_RS12505
Partner locus tags
QCS_RS12500QCS_RS12505
Partner old locus tags
QCS_2551QCS_2552
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890737.1Primary protein accession used for annex mappings.
UniProt accessionA0A069B0L7Primary UniProt accession resolved in the annex database.
UniProt IDA0A069B0L7_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCS_RS12505Primary locus identifier stored in the genes table.
Old locus tagQCS_2552Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHC01000088.1Sequence record reported by the local genomic context database.
Genomic interval27 143-27 850 nt708 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 839-27 850 ntGCF_000449145::NZ_AVHC01000088.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449145::NZ_AVHC01000088.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHC01000088.1All displayed genes belong to this local TCS context.
Neighborhood span25 839-27 850 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 839 nt27 850 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCS_RS12500GCF_000449145#QCS_RS12500
HKClassic

25 839-27 149 nt · Reverse (-)

Old locus QCS_2551RefSeq WP_021362799.1
QCS_RS12505GCF_000449145#QCS_RS12505
RROmpRCurrent focus

27 143-27 850 nt · Reverse (-)

Old locus QCS_2552RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1016365Run 7 · RR · 2196 sequences
Representative sequenceGCF_000003215#QAC_RS0212790Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1016365

Simplified PFAM architecture for RROC_1016365

PFAM domain coverage: 185 / 235 aa (78.7%)

1 aa235 aa
Response_reg: 4-112 aaResponse_regResponse_reg: 4-112 aaResponse_regTrans_reg_C: 151-226 aaTrans_reg_CTrans_reg_C: 151-226 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[4-112] | Trans_reg_C[151-226]
  • Domain count: 2
  • Matched identifier: RROC_1016365
  • Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 151-226 ; Trans_reg_C 151-226
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0212790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 272 · GCF_000449145
AssemblyASM44914v2 · Contighaploid
Genome composition4 011 592 bp · 28,0% GCClostridioides difficile CD51
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key