Gene detail

QCS_RS12500

Histidine kinase, Classic

Clostridioides difficile CD51 · GCF_000449145

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449145#QCS_RS12500Stable P2CS identifier used across views.
GenomeGCF_000449145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113473Run 6 · 255 sequences · id 100% · cov 80%
External referencesWP_021362799.1 · MIST4 QCS_RS12500RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCS_RS12500
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.0000000000642:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:7.07e-25:433:100:109
  • Raw architecture: HisKA:218:0.0000000000642:278:61:64#HATPase_c:334:7.07e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449145::NZ_AVHC01000088.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25839-27850Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCS_2551RefSeq proteinWP_021362799.1
Context group IDGCF_000449145::NZ_AVHC01000088.1::G00039
Context members
QCS_RS12500QCS_RS12505
Partner locus tags
QCS_RS12500QCS_RS12505
Partner old locus tags
QCS_2551QCS_2552
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021362799.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCS_RS12500Primary locus identifier stored in the genes table.
Old locus tagQCS_2551Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHC01000088.1Sequence record reported by the local genomic context database.
Genomic interval25 839-27 149 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 839-27 850 ntGCF_000449145::NZ_AVHC01000088.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449145::NZ_AVHC01000088.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHC01000088.1All displayed genes belong to this local TCS context.
Neighborhood span25 839-27 850 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 839 nt27 850 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCS_RS12500GCF_000449145#QCS_RS12500
HKClassicCurrent focus

25 839-27 149 nt · Reverse (-)

Old locus QCS_2551RefSeq WP_021362799.1
QCS_RS12505GCF_000449145#QCS_RS12505
RROmpR

27 143-27 850 nt · Reverse (-)

Old locus QCS_2552RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113473Run 6 · HK · 255 sequences
Representative sequenceGCF_000448725#QAW_RS13510Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113473

Simplified PFAM architecture for HKOC_2113473

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113473
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS13510

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 255 total members. Page 1 / 6.

GCF_000448725#QAW_RS13510 (representative)
QAW_RS13510 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449085#QCM_RS12580
QCM_RS12580 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449145#QCS_RS12500
QCS_RS12500 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449165#QCU_RS12485
QCU_RS12485 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449345#QEO_RS13070
QEO_RS13070 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449505#QG5_RS13810
QG5_RS13810 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449765#QGU_RS13280
QGU_RS13280 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449865#QI7_RS16320
QI7_RS16320 · HK · Classic
RefSeq: WP_021362799.1
GCF_000449885#QIA_RS13275
QIA_RS13275 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450065#QIU_RS13045
QIU_RS13045 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450565#QMA_RS12995
QMA_RS12995 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450605#QME_RS12960
QME_RS12960 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450825#QOG_RS12630
QOG_RS12630 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450865#QOK_RS13760
QOK_RS13760 · HK · Classic
RefSeq: WP_021362799.1
GCF_000450885#QOM_RS12365
QOM_RS12365 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451085#QSE_RS14090
QSE_RS14090 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451105#QSG_RS14155
QSG_RS14155 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451405#QQ9_RS12950
QQ9_RS12950 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451445#QOQ_RS12285
QOQ_RS12285 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451485#QQ7_RS12205
QQ7_RS12205 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451685#QS5_RS12660
QS5_RS12660 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451805#QSQ_RS05420
QSQ_RS05420 · HK · Classic
RefSeq: WP_021362799.1
GCF_000451845#QSY_RS13020
QSY_RS13020 · HK · Classic
RefSeq: WP_021362799.1
GCF_000530695#BN188_RS12760
BN188_RS12760 · HK · Classic
RefSeq: WP_021362799.1
GCF_001971905#BER39_RS13320
BER39_RS13320 · HK · Classic
RefSeq: WP_021362799.1
GCF_001972005#BER33_RS12780
BER33_RS12780 · HK · Classic
RefSeq: WP_021362799.1
GCF_002300915#BGT99_RS13185
BGT99_RS13185 · HK · Classic
RefSeq: WP_021362799.1
GCF_002300955#BGU00_RS09795
BGU00_RS09795 · HK · Classic
RefSeq: WP_021362799.1
GCF_002301595#BGU31_RS00655
BGU31_RS00655 · HK · Classic
RefSeq: WP_021362799.1
GCF_002301785#BGU42_RS02865
BGU42_RS02865 · HK · Classic
RefSeq: WP_021362799.1
GCF_002301845#BGU46_RS01335
BGU46_RS01335 · HK · Classic
RefSeq: WP_021362799.1
GCF_002301925#BGU51_RS03400
BGU51_RS03400 · HK · Classic
RefSeq: WP_021362799.1
GCF_002302165#BGU92_RS05010
BGU92_RS05010 · HK · Classic
RefSeq: WP_021362799.1
GCF_002303005#BGV16_RS02435
BGV16_RS02435 · HK · Classic
RefSeq: WP_021362799.1
GCF_002304575#BGU17_RS04105
BGU17_RS04105 · HK · Classic
RefSeq: WP_021362799.1
GCF_002812645#CWR54_RS12535
CWR54_RS12535 · HK · Classic
RefSeq: WP_021362799.1
GCF_003863305#EGL80_RS04145
EGL80_RS04145 · HK · Classic
RefSeq: WP_021362799.1
GCF_003932675#EGL78_RS04605
EGL78_RS04605 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314005#E0N82_RS09215
E0N82_RS09215 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314045#E0O11_RS05945
E0O11_RS05945 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314105#E0N78_RS06870
E0N78_RS06870 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314145#E0N80_RS12595
E0N80_RS12595 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314225#E0O08_RS10610
E0O08_RS10610 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314245#E0N90_RS04485
E0N90_RS04485 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314265#E0N96_RS05040
E0N96_RS05040 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314285#E0N97_RS13720
E0N97_RS13720 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314365#E0O16_RS04470
E0O16_RS04470 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314405#E0O07_RS04550
E0O07_RS04550 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314425#E0O25_RS07275
E0O25_RS07275 · HK · Classic
RefSeq: WP_021362799.1
GCF_004314525#E0O40_RS01290
E0O40_RS01290 · HK · Classic
RefSeq: WP_021362799.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 272 · GCF_000449145
AssemblyASM44914v2 · Contighaploid
Genome composition4 011 592 bp · 28,0% GCClostridioides difficile CD51
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key