1 HAMP#1
62-129 aa · 68 aa · 19.7% of protein
Raw token
HAMP:62:0.00000366:129:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCS_RS04705
Histidine kinase, Classic
Clostridioides difficile CD51 · GCF_000449145
ClassHKTypeClassicLength345 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449145#QCS_RS04705Stable P2CS identifier used across views.
GenomeGCF_000449145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length345 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 345 aa (66.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa345 aa
Domain-by-domain annotation3 items
2 HisKA#2
139-197 aa · 59 aa · 17.1% of protein
Raw token
HisKA:139:1.69e-17:197:59:643 HATPase_c#3
245-345 aa · 101 aa · 29.3% of protein
Raw token
HATPase_c:245:6.23e-28:345:106:109- Raw architecture: HAMP:62:0.00000366:129:68:69#HisKA:139:1.69e-17:197:59:64#HATPase_c:245:6.23e-28:345:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449145::NZ_AVHC01000049.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18341-20533Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCS_0959RefSeq proteinWP_021373371.1
Context group ID
GCF_000449145::NZ_AVHC01000049.1::G00014Context members
QCS_RS04700QCS_RS04705
Partner locus tags
QCS_RS04700QCS_RS04705
Partner old locus tags
QCS_0957QCS_0959
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021373371.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCS_RS04705Primary locus identifier stored in the genes table.
Old locus tagQCS_0959Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHC01000049.1Sequence record reported by the local genomic context database.
Genomic interval19 496-20 533 nt1 038 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 341-20 533 ntGCF_000449145::NZ_AVHC01000049.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449145::NZ_AVHC01000049.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHC01000049.1All displayed genes belong to this local TCS context.
Neighborhood span18 341-20 533 nt2 193 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 341 nt20 533 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCS_RS04700GCF_000449145#QCS_RS04700
RROmpR
18 341-19 045 nt · Forward (+)
QCS_RS04705GCF_000449145#QCS_RS04705
HKClassicCurrent focus
19 496-20 533 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449145#QCS_RS04705The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2819222
Simplified PFAM architecture for HKOC_2819222
PFAM domain coverage: 161 / 345 aa (46.7%)
1 aa345 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[137-197] | HATPase_c[245-344]
- Domain count: 2
- Matched identifier: HKOC_2819222
- Positioned domains: HisKA 137-197 ; HATPase_c 245-344
Cluster members and taxonomy
Representative gene: GCF_000449145#QCS_RS04705
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 272 · GCF_000449145
AssemblyASM44914v2 · Contighaploid
Genome composition4 011 592 bp · 28,0% GCClostridioides difficile CD51
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key