1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw token
HisKA:85:0.0000000000009:154:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCQ_RS03780
Histidine kinase, Classic
Clostridioides difficile CD49 · GCF_000449125
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449125#QCQ_RS03780Stable P2CS identifier used across views.
GenomeGCF_000449125Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw token
HATPase_c:201:1.26e-27:304:106:109- Raw architecture: HisKA:85:0.0000000000009:154:70:64#HATPase_c:201:1.26e-27:304:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449125::NZ_AVHB01000027.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17923-19529Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCQ_0742RefSeq proteinWP_021368207.1
Context group ID
GCF_000449125::NZ_AVHB01000027.1::G00012Context members
QCQ_RS03775QCQ_RS03780
Partner locus tags
QCQ_RS03775QCQ_RS03780
Partner old locus tags
QCQ_0741QCQ_0742
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021368207.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8WPU8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8WPU8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCQ_RS03780Primary locus identifier stored in the genes table.
Old locus tagQCQ_0742Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHB01000027.1Sequence record reported by the local genomic context database.
Genomic interval18 612-19 529 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 923-19 529 ntGCF_000449125::NZ_AVHB01000027.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449125::NZ_AVHB01000027.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHB01000027.1All displayed genes belong to this local TCS context.
Neighborhood span17 923-19 529 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 923 nt19 529 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCQ_RS03775GCF_000449125#QCQ_RS03775
RROmpR
17 923-18 612 nt · Forward (+)
QCQ_RS03780GCF_000449125#QCQ_RS03780
HKClassicCurrent focus
18 612-19 529 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448805#QKI_RS03630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882093
Simplified PFAM architecture for HKOC_2882093
PFAM domain coverage: 171 / 305 aa (56.1%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-154] | HATPase_c[201-304]
- Domain count: 2
- Matched identifier: HKOC_2882093
- Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Representative gene: GCF_000448805#QKI_RS03630
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 271 · GCF_000449125
AssemblyASM44912v2 · Contighaploid
Genome composition4 234 199 bp · 28,5% GCClostridioides difficile CD49
Signal transduction countsGenes 98 · HK 46 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key