Gene detail

QCM_RS16065

Histidine kinase, Classic

Clostridioides difficile CD46 · GCF_000449085

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_000449085#QCM_RS16065Stable P2CS identifier used across views.
GenomeGCF_000449085Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676088Run 6 · 404 sequences · id 100% · cov 80%
External referencesWP_009891726.1 · A0AB74R1N1 · MIST4 QCM_RS16065RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCM_RS16065
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.00000000000008:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:4.62e-25:368:110:109
  • Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_000449085::NZ_AVGZ01000031.1::G00051
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span103563-109288Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCM_3272RefSeq proteinWP_009891726.1
Context group IDGCF_000449085::NZ_AVGZ01000031.1::G00051
Context members
QCM_RS16065QCM_RS16070QCM_RS16075QCM_RS16080QCM_RS16085
Partner locus tags
QCM_RS16065QCM_RS16070QCM_RS16075QCM_RS16080QCM_RS16085
Partner old locus tags
QCM_3272QCM_3273QCM_3274QCM_3275QCM_3276

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCM_RS16065Primary locus identifier stored in the genes table.
Old locus tagQCM_3272Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGZ01000031.1Sequence record reported by the local genomic context database.
Genomic interval103 563-104 678 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span103 563-109 288 ntGCF_000449085::NZ_AVGZ01000031.1::G00051

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449085::NZ_AVGZ01000031.1::G00051

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGZ01000031.1All displayed genes belong to this local TCS context.
Neighborhood span103 563-109 288 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
103 563 nt109 288 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

QCM_RS16065GCF_000449085#QCM_RS16065
HKClassicCurrent focus

103 563-104 678 nt · Reverse (-)

Old locus QCM_3272RefSeq WP_009891726.1
QCM_RS16070GCF_000449085#QCM_RS16070
RROmpR

104 714-105 412 nt · Reverse (-)

Old locus QCM_3273RefSeq WP_021363030.1
QCM_RS16075GCF_000449085#QCM_RS16075
RROmpR

105 794-106 474 nt · Reverse (-)

Old locus QCM_3274RefSeq WP_021363031.1
QCM_RS16080GCF_000449085#QCM_RS16080
HKClassic

106 524-108 539 nt · Reverse (-)

Old locus QCM_3275RefSeq WP_021363032.1
QCM_RS16085GCF_000449085#QCM_RS16085
RROmpR

108 611-109 288 nt · Reverse (-)

Old locus QCM_3276RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676088Run 6 · HK · 404 sequences
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676088

Simplified PFAM architecture for HKOC_2676088

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676088
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 269 · GCF_000449085
AssemblyASM44908v2 · Contighaploid
Genome composition4 018 890 bp · 28,5% GCClostridioides difficile CD46
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key