Gene detail

QCM_RS12755

Histidine kinase, Classic

Clostridioides difficile CD46 · GCF_000449085

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449085#QCM_RS12755Stable P2CS identifier used across views.
GenomeGCF_000449085Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0598920Run 6 · 332 sequences · id 100% · cov 80%
External referencesWP_022621102.1 · MIST4 QCM_RS12755RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
HisKA: 558-624 aa (67 aa)1HATPase_c: 671-775 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.66e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000406:775:110:109
  • Raw architecture: HisKA:558:1.66e-18:624:67:64#HATPase_c:671:0.000000000406:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449085::NZ_AVGZ01000029.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span64998-68022Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCM_2593RefSeq proteinWP_022621102.1
Context group IDGCF_000449085::NZ_AVGZ01000029.1::G00041
Context members
QCM_RS12755QCM_RS12760
Partner locus tags
QCM_RS12755QCM_RS12760
Partner old locus tags
QCM_2593QCM_2594
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022621102.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCM_RS12755Primary locus identifier stored in the genes table.
Old locus tagQCM_2593Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGZ01000029.1Sequence record reported by the local genomic context database.
Genomic interval64 998-67 334 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span64 998-68 022 ntGCF_000449085::NZ_AVGZ01000029.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449085::NZ_AVGZ01000029.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGZ01000029.1All displayed genes belong to this local TCS context.
Neighborhood span64 998-68 022 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
64 998 nt68 022 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCM_RS12755GCF_000449085#QCM_RS12755
HKClassicCurrent focus

64 998-67 334 nt · Reverse (-)

Old locus QCM_2593RefSeq WP_022621102.1
QCM_RS12760GCF_000449085#QCM_RS12760
RROmpR

67 306-68 022 nt · Reverse (-)

Old locus QCM_2594RefSeq WP_003431132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0598920Run 6 · HK · 332 sequences
Representative sequenceGCF_000242355#MUI_RS0115490Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0598920

Simplified PFAM architecture for HKOC_0598920

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0598920
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0115490

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 269 · GCF_000449085
AssemblyASM44908v2 · Contighaploid
Genome composition4 018 890 bp · 28,5% GCClostridioides difficile CD46
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key