1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw token
HisKA_3:188:4.07e-20:253:67:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCM_RS05960
Histidine kinase, Classic
Clostridioides difficile CD46 · GCF_000449085
ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449085#QCM_RS05960Stable P2CS identifier used across views.
GenomeGCF_000449085Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw token
HATPase_c:294:0.00000000019:378:104:109- Raw architecture: HisKA_3:188:4.07e-20:253:67:68#HATPase_c:294:0.00000000019:378:104:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449085::NZ_AVGZ01000018.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span260071-261874Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCM_1206RefSeq proteinWP_009896183.1
Context group ID
GCF_000449085::NZ_AVGZ01000018.1::G00018Context members
QCM_RS05955QCM_RS05960
Partner locus tags
QCM_RS05955QCM_RS05960
Partner old locus tags
QCM_1205QCM_1206
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009896183.1Primary protein accession used for annex mappings.
UniProt accessionQ18BD5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BD5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCM_RS05960Primary locus identifier stored in the genes table.
Old locus tagQCM_1206Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGZ01000018.1Sequence record reported by the local genomic context database.
Genomic interval260 711-261 874 nt1 164 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span260 071-261 874 ntGCF_000449085::NZ_AVGZ01000018.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449085::NZ_AVGZ01000018.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGZ01000018.1All displayed genes belong to this local TCS context.
Neighborhood span260 071-261 874 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
260 071 nt261 874 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCM_RS05955GCF_000449085#QCM_RS05955
RRNarL
260 071-260 718 nt · Reverse (-)
QCM_RS05960GCF_000449085#QCM_RS05960
HKClassicCurrent focus
260 711-261 874 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS07055Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2550063
Simplified PFAM architecture for HKOC_2550063
PFAM domain coverage: 150 / 387 aa (38.8%)
1 aa387 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
- Domain count: 2
- Matched identifier: HKOC_2550063
- Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS07055
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 269 · GCF_000449085
AssemblyASM44908v2 · Contighaploid
Genome composition4 018 890 bp · 28,5% GCClostridioides difficile CD46
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key