Gene detail

QCI_RS09275

Histidine kinase, Classic

Clostridioides difficile CD44 · GCF_000449045

ClassHKTypeClassicLength900 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449045#QCI_RS09275Stable P2CS identifier used across views.
GenomeGCF_000449045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0405722Run 6 · 21 sequences · id 100% · cov 80% · representative
External referencesWP_021371248.1 · MIST4 QCI_RS09275RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length900 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 900 aa (57.1%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa900 aa
KdpD: 22-230 aa (209 aa)1GAF_3: 533-656 aa (124 aa)2HisKA: 676-743 aa (68 aa)3HATPase_c: 787-899 aa (113 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:7.83e-134:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.00000594:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.00000000000628:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:2.1e-30:899:113:109
  • Raw architecture: KdpD:22:7.83e-134:230:209:210#GAF_3:533:0.00000594:656:129:129#HisKA:676:0.00000000000628:743:68:64#HATPase_c:787:2.1e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449045::NZ_AVGX01000127.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span19356-22790Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCI_1802RefSeq proteinWP_021371248.1
Context group IDGCF_000449045::NZ_AVGX01000127.1::G00032
Context members
QCI_RS09275QCI_RS09280
Partner locus tags
QCI_RS09275QCI_RS09280
Partner old locus tags
QCI_1802QCI_1803
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021371248.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCI_RS09275Primary locus identifier stored in the genes table.
Old locus tagQCI_1802Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGX01000127.1Sequence record reported by the local genomic context database.
Genomic interval19 356-22 058 nt2 703 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span19 356-22 790 ntGCF_000449045::NZ_AVGX01000127.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449045::NZ_AVGX01000127.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGX01000127.1All displayed genes belong to this local TCS context.
Neighborhood span19 356-22 790 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 356 nt22 790 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCI_RS09275GCF_000449045#QCI_RS09275
HKClassicCurrent focus

19 356-22 058 nt · Forward (+)

Old locus QCI_1802RefSeq WP_021371248.1
QCI_RS09280GCF_000449045#QCI_RS09280
RROmpR

22 092-22 790 nt · Forward (+)

Old locus QCI_1803RefSeq WP_003439430.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0405722Run 6 · HK · 21 sequences
Representative sequenceGCF_000449045#QCI_RS09275The current gene is the representative for this cluster.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0405722

Simplified PFAM architecture for HKOC_0405722

PFAM domain coverage: 494 / 900 aa (54.9%)

1 aa900 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0405722
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449045#QCI_RS09275

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 21 over 21 total members. Page 1 / 1.

GCF_000449045#QCI_RS09275 (representative)
QCI_RS09275 · HK · Classic
RefSeq: WP_021371248.1
GCF_000449785#QGW_RS09685
QGW_RS09685 · HK · Classic
RefSeq: WP_021371248.1
GCF_000632735#BG47_RS08400
BG47_RS08400 · HK · Classic
RefSeq: WP_021371248.1
GCF_003862975#EGL86_RS02175
EGL86_RS02175 · HK · Classic
RefSeq: WP_021371248.1
GCF_004317645#E0Q60_RS13625
E0Q60_RS13625 · HK · Classic
RefSeq: WP_021371248.1
GCF_004318405#E0R07_RS17525
E0R07_RS17525 · HK · Classic
RefSeq: WP_021371248.1
GCF_004318425#E0Q86_RS17965
E0Q86_RS17965 · HK · Classic
RefSeq: WP_021371248.1
GCF_007114815#FLH90_RS03630
FLH90_RS03630 · HK · Classic
RefSeq: WP_021371248.1
GCF_007114825#FLH89_RS03630
FLH89_RS03630 · HK · Classic
RefSeq: WP_021371248.1
GCF_007114835#FLH39_RS01745
FLH39_RS01745 · HK · Classic
RefSeq: WP_021371248.1
GCF_025532375#H3T49_RS01120
H3T49_RS01120 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533315#H3U39_RS01125
H3U39_RS01125 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533375#H3U37_RS01750
H3U37_RS01750 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533715#H3U59_RS01795
H3U59_RS01795 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533795#H3U65_RS01790
H3U65_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533815#H3U70_RS01790
H3U70_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533875#H3U67_RS01790
H3U67_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533905#H3U60_RS01790
H3U60_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533935#H3U71_RS01790
H3U71_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_025533955#H3U68_RS01790
H3U68_RS01790 · HK · Classic
RefSeq: WP_021371248.1
GCF_036699055#LFA99_RS03165
LFA99_RS03165 · HK · Classic
RefSeq: WP_021371248.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 267 · GCF_000449045
AssemblyASM44904v2 · Contighaploid
Genome composition3 994 115 bp · 28,5% GCClostridioides difficile CD44
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key