Gene detail

QCG_RS12385

Histidine kinase, Classic

Clostridioides difficile CD43 · GCF_000449025

ClassHKTypeClassicLength368 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000449025#QCG_RS12385Stable P2CS identifier used across views.
GenomeGCF_000449025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1351418Run 6 · 59 sequences · id 100% · cov 80%
External referencesWP_021417276.1 · MIST4 QCG_RS12385RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length368 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 368 aa (41.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCG_RS12385
Domain-by-domain annotation2 items
1 HisKA#1
147-213 aa · 67 aa · 18.2% of protein
Raw tokenHisKA:147:0.0000000000000132:213:67:64
2 HATPase_c#2
266-351 aa · 86 aa · 23.4% of protein
Raw tokenHATPase_c:266:0.0000000433:351:90:109
  • Raw architecture: HisKA:147:0.0000000000000132:213:67:64#HATPase_c:266:0.0000000433:351:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000449025::NZ_AVGW01000072.1::G00039
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1109Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCG_2507RefSeq proteinWP_021417276.1
Context group IDGCF_000449025::NZ_AVGW01000072.1::G00039
Context members
QCG_RS12385
Partner locus tags
QCG_RS12385
Partner old locus tags
QCG_2507
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021417276.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCG_RS12385Primary locus identifier stored in the genes table.
Old locus tagQCG_2507Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGW01000072.1Sequence record reported by the local genomic context database.
Genomic interval1-1 109 nt1 109 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 109 ntGCF_000449025::NZ_AVGW01000072.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449025::NZ_AVGW01000072.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGW01000072.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 109 nt1 109 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 109 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QCG_RS12385GCF_000449025#QCG_RS12385
HKClassicCurrent focus

1-1 109 nt · Forward (+)

Old locus QCG_2507RefSeq WP_021417276.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1351418Run 6 · HK · 59 sequences
Representative sequenceGCF_900243095#DBQ06_RS06465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1351418

Simplified PFAM architecture for HKOC_1351418

PFAM domain coverage: 191 / 532 aa (35.9%)

1 aa532 aa
HAMP: 257-297 aaHAMPHisKA: 312-377 aaHisKAHATPase_c: 429-512 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[257-297] | HisKA[312-377] | HATPase_c[429-512]
  • Domain count: 3
  • Matched identifier: HKOC_1351418
  • Positioned domains: HAMP 257-297 ; HisKA 312-377 ; HATPase_c 429-512
Cluster members and taxonomy
Visualization

Representative gene: GCF_900243095#DBQ06_RS06465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 266 · GCF_000449025
AssemblyASM44902v2 · Contighaploid
Genome composition4 329 033 bp · 28,0% GCClostridioides difficile CD43
Signal transduction countsGenes 99 · HK 46 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key