Gene detail

QCG_RS12260

Histidine kinase, Classic

Clostridioides difficile CD43 · GCF_000449025

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449025#QCG_RS12260Stable P2CS identifier used across views.
GenomeGCF_000449025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0800915Run 6 · 909 sequences · id 100% · cov 80%
External referencesWP_009897457.1 · A0AB74Q9S7 · MIST4 QCG_RS12260RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCG_RS12260
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000203:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000196:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000203:524:68:64#HATPase_c:570:0.00000000000196:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449025::NZ_AVGW01000070.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21168-24116Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCG_2484RefSeq proteinWP_009897457.1
Context group IDGCF_000449025::NZ_AVGW01000070.1::G00037
Context members
QCG_RS12260QCG_RS12270
Partner locus tags
QCG_RS12260QCG_RS12270
Partner old locus tags
QCG_2484QCG_2485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009897457.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74Q9S7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74Q9S7_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCG_RS12260Primary locus identifier stored in the genes table.
Old locus tagQCG_2484Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGW01000070.1Sequence record reported by the local genomic context database.
Genomic interval21 168-23 228 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span21 168-24 116 ntGCF_000449025::NZ_AVGW01000070.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449025::NZ_AVGW01000070.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGW01000070.1All displayed genes belong to this local TCS context.
Neighborhood span21 168-24 116 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 168 nt24 116 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCG_RS12260GCF_000449025#QCG_RS12260
HKClassicCurrent focus

21 168-23 228 nt · Reverse (-)

Old locus QCG_2484RefSeq WP_009897457.1
QCG_RS12270GCF_000449025#QCG_RS12270
RROmpR

23 424-24 116 nt · Reverse (-)

Old locus QCG_2485RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0800915Run 6 · HK · 909 sequences
Representative sequenceGCF_000009205#CD630_RS12360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0800915

Simplified PFAM architecture for HKOC_0800915

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0800915
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS12360

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 266 · GCF_000449025
AssemblyASM44902v2 · Contighaploid
Genome composition4 329 033 bp · 28,0% GCClostridioides difficile CD43
Signal transduction countsGenes 99 · HK 46 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key