Gene detail

QCC_RS07825

Histidine kinase, Classic

Clostridioides difficile CD41 · GCF_000448985

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448985#QCC_RS07825Stable P2CS identifier used across views.
GenomeGCF_000448985Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747926Run 6 · 189 sequences · id 100% · cov 80%
External referencesWP_004454490.1 · A0A6N3HD92 · MIST4 QCC_RS07825RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.00000391:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000199:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:9.9e-27:465:108:109
  • Raw architecture: HAMP:166:0.00000391:232:69:69#HisKA:245:0.0000000000000199:312:68:64#HATPase_c:359:9.9e-27:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448985::NZ_AVGU01000019.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span51851-53983Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCC_1584RefSeq proteinWP_004454490.1
Context group IDGCF_000448985::NZ_AVGU01000019.1::G00025
Context members
QCC_RS07820QCC_RS07825
Partner locus tags
QCC_RS07820QCC_RS07825
Partner old locus tags
QCC_1583QCC_1584
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454490.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3HD92Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3HD92_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCC_RS07825Primary locus identifier stored in the genes table.
Old locus tagQCC_1584Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGU01000019.1Sequence record reported by the local genomic context database.
Genomic interval52 580-53 983 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span51 851-53 983 ntGCF_000448985::NZ_AVGU01000019.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448985::NZ_AVGU01000019.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGU01000019.1All displayed genes belong to this local TCS context.
Neighborhood span51 851-53 983 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
51 851 nt53 983 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCC_RS07820GCF_000448985#QCC_RS07820
RROmpR

51 851-52 576 nt · Forward (+)

Old locus QCC_1583RefSeq WP_004454491.1
QCC_RS07825GCF_000448985#QCC_RS07825
HKClassicCurrent focus

52 580-53 983 nt · Forward (+)

Old locus QCC_1584RefSeq WP_004454490.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747926Run 6 · HK · 189 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS03855Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747926

Simplified PFAM architecture for HKOC_1747926

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747926
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS03855

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 264 · GCF_000448985
AssemblyASM44898v2 · Contighaploid
Genome composition4 024 429 bp · 28,5% GCClostridioides difficile CD41
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key