Gene detail

QCA_RS18285

Histidine kinase, Classic

Clostridioides difficile CD40 · GCF_000448965

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448965#QCA_RS18285Stable P2CS identifier used across views.
GenomeGCF_000448965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503301Run 6 · 110 sequences · id 100% · cov 80%
External referencesWP_009898786.1 · MIST4 QCA_RS18285RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCA_RS18285
Domain-by-domain annotation2 items
1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw tokenHisKA:168:0.000000000000454:234:67:64
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw tokenHATPase_c:280:2.77e-26:388:110:109
  • Raw architecture: HisKA:168:0.000000000000454:234:67:64#HATPase_c:280:2.77e-26:388:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448965::NZ_AVGT01000090.1::G00056
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12698-14561Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCA_3757RefSeq proteinWP_009898786.1
Context group IDGCF_000448965::NZ_AVGT01000090.1::G00056
Context members
QCA_RS18285QCA_RS18290
Partner locus tags
QCA_RS18285QCA_RS18290
Partner old locus tags
QCA_3757QCA_3758
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009898786.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCA_RS18285Primary locus identifier stored in the genes table.
Old locus tagQCA_3757Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGT01000090.1Sequence record reported by the local genomic context database.
Genomic interval12 698-13 879 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span12 698-14 561 ntGCF_000448965::NZ_AVGT01000090.1::G00056

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448965::NZ_AVGT01000090.1::G00056

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGT01000090.1All displayed genes belong to this local TCS context.
Neighborhood span12 698-14 561 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 698 nt14 561 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCA_RS18285GCF_000448965#QCA_RS18285
HKClassicCurrent focus

12 698-13 879 nt · Reverse (-)

Old locus QCA_3757RefSeq WP_009898786.1
QCA_RS18290GCF_000448965#QCA_RS18290
RROmpR

13 869-14 561 nt · Reverse (-)

Old locus QCA_3758RefSeq WP_003435805.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503301Run 6 · HK · 110 sequences
Representative sequenceGCF_000154625#QAB_RS0220710Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503301

Simplified PFAM architecture for HKOC_2503301

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503301
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0220710

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 263 · GCF_000448965
AssemblyASM44896v2 · Contighaploid
Genome composition4 069 381 bp · 28,5% GCClostridioides difficile CD40
Signal transduction countsGenes 96 · HK 46 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key