Gene detail

QCA_RS12215

Histidine kinase, Classic

Clostridioides difficile CD40 · GCF_000448965

ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448965#QCA_RS12215Stable P2CS identifier used across views.
GenomeGCF_000448965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359697Run 6 · 26 sequences · id 100% · cov 80%
External referencesWP_009897499.1 · MIST4 QCA_RS12215RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 529 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCA_RS12215
Domain-by-domain annotation2 items
1 HisKA#1
308-374 aa · 67 aa · 12.7% of protein
Raw tokenHisKA:308:0.0000000000000174:374:67:64
2 HATPase_c#2
427-512 aa · 86 aa · 16.3% of protein
Raw tokenHATPase_c:427:0.0000000443:512:90:109
  • Raw architecture: HisKA:308:0.0000000000000174:374:67:64#HATPase_c:427:0.0000000443:512:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448965::NZ_AVGT01000070.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5396-7670Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCA_2501RefSeq proteinWP_009897499.1
Context group IDGCF_000448965::NZ_AVGT01000070.1::G00038
Context members
QCA_RS12210QCA_RS12215
Partner locus tags
QCA_RS12210QCA_RS12215
Partner old locus tags
QCA_2500QCA_2501
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009897499.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCA_RS12215Primary locus identifier stored in the genes table.
Old locus tagQCA_2501Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGT01000070.1Sequence record reported by the local genomic context database.
Genomic interval6 081-7 670 nt1 590 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 396-7 670 ntGCF_000448965::NZ_AVGT01000070.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448965::NZ_AVGT01000070.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGT01000070.1All displayed genes belong to this local TCS context.
Neighborhood span5 396-7 670 nt2 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 396 nt7 670 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCA_RS12210GCF_000448965#QCA_RS12210
RROmpR

5 396-6 112 nt · Forward (+)

Old locus QCA_2500RefSeq WP_004454617.1
QCA_RS12215GCF_000448965#QCA_RS12215
HKClassicCurrent focus

6 081-7 670 nt · Forward (+)

Old locus QCA_2501RefSeq WP_009897499.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359697Run 6 · HK · 26 sequences
Representative sequenceGCF_000154625#QAB_RS0213940Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359697

Simplified PFAM architecture for HKOC_1359697

PFAM domain coverage: 191 / 529 aa (36.1%)

1 aa529 aa
HAMP: 254-294 aaHAMPHisKA: 309-374 aaHisKAHATPase_c: 426-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
  • Domain count: 3
  • Matched identifier: HKOC_1359697
  • Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0213940

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 263 · GCF_000448965
AssemblyASM44896v2 · Contighaploid
Genome composition4 069 381 bp · 28,5% GCClostridioides difficile CD40
Signal transduction countsGenes 96 · HK 46 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key