1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw token
HisKA:196:0.0000000000161:260:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCA_RS11170
Histidine kinase, Classic
Clostridioides difficile CD40 · GCF_000448965
ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448965#QCA_RS11170Stable P2CS identifier used across views.
GenomeGCF_000448965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw token
HATPase_c:307:1.45e-18:424:119:109- Raw architecture: HisKA:196:0.0000000000161:260:65:64#HATPase_c:307:1.45e-18:424:119:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000448965::NZ_AVGT01000065.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24321-26250Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCA_2291RefSeq proteinWP_003434036.1
Context group ID
GCF_000448965::NZ_AVGT01000065.1::G00036Context members
QCA_RS11170QCA_RS11175
Partner locus tags
QCA_RS11170QCA_RS11175
Partner old locus tags
QCA_2291QCA_2292
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434036.1Primary protein accession used for annex mappings.
UniProt accessionQ185Q2Primary UniProt accession resolved in the annex database.
UniProt IDQ185Q2_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCA_RS11170Primary locus identifier stored in the genes table.
Old locus tagQCA_2291Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGT01000065.1Sequence record reported by the local genomic context database.
Genomic interval24 321-25 598 nt1 278 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span24 321-26 250 ntGCF_000448965::NZ_AVGT01000065.1::G00036
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000448965::NZ_AVGT01000065.1::G00036Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGT01000065.1All displayed genes belong to this local TCS context.
Neighborhood span24 321-26 250 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 321 nt26 250 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCA_RS11170GCF_000448965#QCA_RS11170
HKClassicCurrent focus
24 321-25 598 nt · Reverse (-)
QCA_RS11175GCF_000448965#QCA_RS11175
RROmpR
25 582-26 250 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS11460Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2215987
Simplified PFAM architecture for HKOC_2215987
PFAM domain coverage: 179 / 425 aa (42.1%)
1 aa425 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[197-260] | HATPase_c[308-422]
- Domain count: 2
- Matched identifier: HKOC_2215987
- Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS11460
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 263 · GCF_000448965
AssemblyASM44896v2 · Contighaploid
Genome composition4 069 381 bp · 28,5% GCClostridioides difficile CD40
Signal transduction countsGenes 96 · HK 46 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key