Gene detail

QAQ_RS02275

Histidine kinase, Classic

Clostridioides difficile CD8 · GCF_000448845

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448845#QAQ_RS02275Stable P2CS identifier used across views.
GenomeGCF_000448845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674086Run 6 · 679 sequences · id 100% · cov 80%
External referencesWP_003434751.1 · Q188S3 · MIST4 QAQ_RS02275RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000139:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000206:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.74e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000139:238:78:69#HisKA:250:0.00000000206:315:66:64#HATPase_c:365:2.74e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448845::NZ_AVGJ01000025.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41126-43261Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQAQ_0457RefSeq proteinWP_003434751.1
Context group IDGCF_000448845::NZ_AVGJ01000025.1::G00003
Context members
QAQ_RS02270QAQ_RS02275
Partner locus tags
QAQ_RS02270QAQ_RS02275
Partner old locus tags
QAQ_0456QAQ_0457
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434751.1Primary protein accession used for annex mappings.
UniProt accessionQ188S3Primary UniProt accession resolved in the annex database.
UniProt IDQ188S3_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAQ_RS02275Primary locus identifier stored in the genes table.
Old locus tagQAQ_0457Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGJ01000025.1Sequence record reported by the local genomic context database.
Genomic interval41 837-43 261 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 126-43 261 ntGCF_000448845::NZ_AVGJ01000025.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448845::NZ_AVGJ01000025.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGJ01000025.1All displayed genes belong to this local TCS context.
Neighborhood span41 126-43 261 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 126 nt43 261 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAQ_RS02270GCF_000448845#QAQ_RS02270
RROmpR

41 126-41 818 nt · Forward (+)

Old locus QAQ_0456RefSeq WP_003434748.1
QAQ_RS02275GCF_000448845#QAQ_RS02275
HKClassicCurrent focus

41 837-43 261 nt · Forward (+)

Old locus QAQ_0457RefSeq WP_003434751.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674086Run 6 · HK · 679 sequences
Representative sequenceGCF_000009205#CD630_RS02960Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674086

Simplified PFAM architecture for HKOC_1674086

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674086
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS02960

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 253 · GCF_000448845
AssemblyASM44884v2 · Contighaploid
Genome composition4 044 267 bp · 28,5% GCClostridioides difficile CD8
Signal transduction countsGenes 93 · HK 45 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key