Gene detail

QC5_RS08945

Response regulator NtrC family

Clostridioides difficile CD34 · GCF_000448765

ClassRRTypeNtrCLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448765#QC5_RS08945Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0334039Run 7 · 94 sequences · id 100% · cov 80% · representative
External referencesWP_021366703.1 · A0A069A0G8 · MIST4 QC5_RS08945RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 440 aa (61.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QC5_RS08945
Domain-by-domain annotation3 items
1 Response_reg#1
3-114 aa · 112 aa · 25.5% of protein
Raw tokenResponse_reg:3:1.09e-25:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 27.0% of protein
Raw tokenAAA_5:157:0.00000000298:275:128:135
3 HTH_8#3
398-437 aa · 40 aa · 9.1% of protein
Raw tokenHTH_8:398:0.000000000178:437:40:40
  • Raw architecture: Response_reg:3:1.09e-25:114:112:111#AAA_5:157:0.00000000298:275:128:135#HTH_8:398:0.000000000178:437:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448765::NZ_AVGQ01000033.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67567-70883Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_1798RefSeq proteinWP_021366703.1
Context group IDGCF_000448765::NZ_AVGQ01000033.1::G00028
Context members
QC5_RS08940QC5_RS08945
Partner locus tags
QC5_RS08940QC5_RS08945
Partner old locus tags
QC5_1797QC5_1798
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366703.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A0G8Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A0G8_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC5_RS08945Primary locus identifier stored in the genes table.
Old locus tagQC5_1798Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000033.1Sequence record reported by the local genomic context database.
Genomic interval69 561-70 883 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span67 567-70 883 ntGCF_000448765::NZ_AVGQ01000033.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448765::NZ_AVGQ01000033.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000033.1All displayed genes belong to this local TCS context.
Neighborhood span67 567-70 883 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 567 nt70 883 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC5_RS08940GCF_000448765#QC5_RS08940
HKClassic

67 567-69 561 nt · Forward (+)

Old locus QC5_1797RefSeq WP_021366718.1
QC5_RS08945GCF_000448765#QC5_RS08945
RRNtrCCurrent focus

69 561-70 883 nt · Forward (+)

Old locus QC5_1798RefSeq WP_021366703.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0334039Run 7 · RR · 94 sequences
Representative sequenceGCF_000448765#QC5_RS08945The current gene is the representative for this cluster.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0334039

Simplified PFAM architecture for RROC_0334039

PFAM domain coverage: 386 / 440 aa (87.7%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regResponse_reg: 3-113 aaResponse_regSigma54_activat: 137-300 aaSigma54_activatSigma54_activat: 137-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14AAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[137-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0334039
  • Positioned domains: Response_reg 3-113 ; Response_reg 3-113 ; Sigma54_activat 137-300 ; Sigma54_activat 137-300 ; AAA_lid_14 306-375 ; AAA_lid_14 306-375 ; HTH_8 397-437 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS08945

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 94 total members. Page 1 / 2.

GCF_000448765#QC5_RS08945 (representative)
QC5_RS08945 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000449705#QGM_RS09060
QGM_RS09060 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000452265#C673_RS08875
C673_RS08875 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000452285#C674_RS08635
C674_RS08635 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000452305#C675_RS08985
C675_RS08985 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000452325#C676_RS09005
C676_RS09005 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000473605#QSW_RS09040
QSW_RS09040 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000586575#Y779_RS0108860
Y779_RS0108860 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_000939295#BN1097_RS04085
BN1097_RS04085 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_001192735#AWU81_RS06270
AWU81_RS06270 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_001263655#AWU80_RS01965
AWU80_RS01965 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_001263675#AWU78_RS02350
AWU78_RS02350 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_001263695#AWU79_RS07100
AWU79_RS07100 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_002301075#BGU05_RS07685
BGU05_RS07685 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_002301105#BGU08_RS12235
BGU08_RS12235 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_002303125#BGV22_RS13825
BGV22_RS13825 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_003481905#CDIF29688_RS10210
CDIF29688_RS10210 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004314925#E0O72_RS14430
E0O72_RS14430 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004315705#E0P69_RS13715
E0P69_RS13715 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004315945#E0P54_RS00110
E0P54_RS00110 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004316725#E0Q14_RS12510
E0Q14_RS12510 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004317945#E0Q65_RS15715
E0Q65_RS15715 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_004318205#E0Q88_RS11580
E0Q88_RS11580 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_007000675#D1N83_RS03420
D1N83_RS03420 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_007000845#D1N73_RS09825
D1N73_RS09825 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_007000915#D1N70_RS10190
D1N70_RS10190 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_007000925#D1N68_RS15405
D1N68_RS15405 · RR · NtrC
RefSeq: WP_142795620.1
GCF_007000965#D1N69_RS06650
D1N69_RS06650 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_007001195#D1N57_RS13670
D1N57_RS13670 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_012030135#GSQ49_RS07275
GSQ49_RS07275 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_017310965#JQS20_RS06825
JQS20_RS06825 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_019426605#K1N11_RS04470
K1N11_RS04470 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_021283725#LWE87_RS08805
LWE87_RS08805 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_021283905#LWE93_RS13935
LWE93_RS13935 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_021284005#LWE88_RS08235
LWE88_RS08235 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_024451165#NO136_RS08095
NO136_RS08095 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_025135955#CDIF104450_RS10030
CDIF104450_RS10030 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_025533115#H3U19_RS11140
H3U19_RS11140 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_026337815#OSC44_RS08590
OSC44_RS08590 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_030251745#QQO64_RS02580
QQO64_RS02580 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_034188805#SQ131_RS15280
SQ131_RS15280 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_036698425#LFB09_RS14805
LFB09_RS14805 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_036698795#LFB08_RS14805
LFB08_RS14805 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_042876425#ACFYIC_RS04635
ACFYIC_RS04635 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_043107605#ACGAK4_RS12155
ACGAK4_RS12155 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_043107725#ACGAK8_RS10415
ACGAK8_RS10415 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_900008635#A4001_RS10815
A4001_RS10815 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_900009405#A4055_RS13380
A4055_RS13380 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_900009805#A4Y97_RS04935
A4Y97_RS04935 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8
GCF_900014165#A4Y33_RS10335
A4Y33_RS10335 · RR · NtrC
RefSeq: WP_021366703.1
UniProt: A0A069A0G8

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key