1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw token
HAMP:166:0.0000042:232:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QC5_RS08595
Histidine kinase, Classic
Clostridioides difficile CD34 · GCF_000448765
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000448765#QC5_RS08595Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 467 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
245-309 aa · 65 aa · 13.9% of protein
Raw token
HisKA:245:0.0000000000000154:309:65:643 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw token
HATPase_c:359:1.25e-26:465:108:109- Raw architecture: HAMP:166:0.0000042:232:69:69#HisKA:245:0.0000000000000154:309:65:64#HATPase_c:359:1.25e-26:465:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000448765::NZ_AVGQ01000033.1::G00026
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span4876-6279Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_1729RefSeq proteinWP_021366728.1
Context group ID
GCF_000448765::NZ_AVGQ01000033.1::G00026Context members
QC5_RS08595
Partner locus tags
QC5_RS08595
Partner old locus tags
QC5_1729
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021366728.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A076Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A076_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQC5_RS08595Primary locus identifier stored in the genes table.
Old locus tagQC5_1729Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000033.1Sequence record reported by the local genomic context database.
Genomic interval4 876-6 279 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 876-6 279 ntGCF_000448765::NZ_AVGQ01000033.1::G00026
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000448765::NZ_AVGQ01000033.1::G00026Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000033.1All displayed genes belong to this local TCS context.
Neighborhood span4 876-6 279 nt1 404 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 876 nt6 279 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
QC5_RS08595GCF_000448765#QC5_RS08595
HKClassicCurrent focus
4 876-6 279 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448765#QC5_RS08595The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1748387
Simplified PFAM architecture for HKOC_1748387
PFAM domain coverage: 171 / 467 aa (36.6%)
1 aa467 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-308] | HATPase_c[359-465]
- Domain count: 2
- Matched identifier: HKOC_1748387
- Positioned domains: HisKA 245-308 ; HATPase_c 359-465
Cluster members and taxonomy
Representative gene: GCF_000448765#QC5_RS08595
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key